Coupled homologous and nonhomologous repair of a double-strand break preserves genomic integrity in mammalian cells.
Richardson C, Jasin M.
Richardson C, et al. Among authors: jasin m.
Mol Cell Biol. 2000 Dec;20(23):9068-75. doi: 10.1128/MCB.20.23.9068-9075.2000.
Mol Cell Biol. 2000.
PMID: 11074004
Free PMC article.
Using a mouse embryonic stem cell system, we previously demonstrated that a DSB in one chromosome can be repaired by recombination with a homologous sequence on a heterologous chromosome, without any evidence of genome rearrangements (C. Richardson, M. E. Moynahan, and …
Using a mouse embryonic stem cell system, we previously demonstrated that a DSB in one chromosome can be repaired by recombination with a ho …