Lambden S - Search Results

1

Definitions and pathophysiology of vasoplegic shock.

Lambden S, Creagh-Brown BC, Hunt J, Summers C, Forni LG. Lambden S, et al. Crit Care. 2018 Jul 6;22(1):174. doi: 10.1186/s13054-018-2102-1. Crit Care. 2018. PMID: 29980217 Free PMC article. Review.

2

Evidence for a protective role for the rs805305 single nucleotide polymorphism of dimethylarginine dimethylaminohydrolase 2 (DDAH2) in septic shock through the regulation of DDAH activity.

Lambden S, Tomlinson J, Piper S, Gordon AC, Leiper J. Lambden S, et al. Crit Care. 2018 Dec 11;22(1):336. doi: 10.1186/s13054-018-2277-5. Crit Care. 2018. PMID: 30538005 Free PMC article.

3

Endothelial cell regulation of systemic haemodynamics and metabolism acts through the HIF transcription factors.

Lambden S, Cowburn AS, Macias D, Garrud TAC, Krause BJ, Giussani DA, Summers C, Johnson RS. Lambden S, et al. Intensive Care Med Exp. 2021 Jun 11;9(1):28. doi: 10.1186/s40635-021-00390-y. Intensive Care Med Exp. 2021. PMID: 34114090 Free PMC article.

4

The SOFA score-development, utility and challenges of accurate assessment in clinical trials.

Lambden S, Laterre PF, Levy MM, Francois B. Lambden S, et al. Crit Care. 2019 Nov 27;23(1):374. doi: 10.1186/s13054-019-2663-7. Crit Care. 2019. PMID: 31775846 Free PMC article. Review.

5

Pharmacological inhibition of DDAH1 improves survival, haemodynamics and organ function in experimental septic shock.

Wang Z, Lambden S, Taylor V, Sujkovic E, Nandi M, Tomlinson J, Dyson A, McDonald N, Caddick S, Singer M, Leiper J. Wang Z, et al. Among authors: lambden s. Biochem J. 2014 Jun 1;460(2):309-16. doi: 10.1042/BJ20131666. Biochem J. 2014. PMID: 24611830

6

Rapid onset of severe septic shock in the pregnant mouse†.

Zöllner J, Lambden S, Nasri NM, Leiper J, Johnson MR. Zöllner J, et al. Among authors: lambden s. Biol Reprod. 2019 Feb 1;100(2):505-513. doi: 10.1093/biolre/ioy193. Biol Reprod. 2019. PMID: 30184059 Free article.

7

Hypoxia causes increased monocyte nitric oxide synthesis which is mediated by changes in dimethylarginine dimethylaminohydrolase 2 expression in animal and human models of normobaric hypoxia.

Lambden S, Martin D, Vanezis K, Lee B, Tomlinson J, Piper S, Boruc O, Mythen M, Leiper J. Lambden S, et al. Nitric Oxide. 2016 Aug 31;58:59-66. doi: 10.1016/j.niox.2016.06.003. Epub 2016 Jun 16. Nitric Oxide. 2016. PMID: 27319282 Free article.

8

Dimethylarginine dimethylaminohydrolase 2 regulates nitric oxide synthesis and hemodynamics and determines outcome in polymicrobial sepsis.

Lambden S, Kelly P, Ahmetaj-Shala B, Wang Z, Lee B, Nandi M, Torondel B, Delahaye M, Dowsett L, Piper S, Tomlinson J, Caplin B, Colman L, Boruc O, Slaviero A, Zhao L, Oliver E, Khadayate S, Singer M, Arrigoni F, Leiper J. Lambden S, et al. Arterioscler Thromb Vasc Biol. 2015 Jun;35(6):1382-92. doi: 10.1161/ATVBAHA.115.305278. Epub 2015 Apr 9. Arterioscler Thromb Vasc Biol. 2015. PMID: 25857313

9

Inhibition of Dimethylarginine Dimethylaminohydrolase 1 Improves the Outcome of Sepsis in Pregnant Mice.

Zölner J, Lambden S, Nasri NM, Johnson MR, Leiper J. Zölner J, et al. Among authors: lambden s. Shock. 2020 Oct;54(4):498-506. doi: 10.1097/SHK.0000000000001490. Shock. 2020. PMID: 31821207

10

2-Hydroxyglutarate Metabolism Is Altered in an in vivo Model of LPS Induced Endotoxemia.

Fitzpatrick SF, Lambden S, Macias D, Puthucheary Z, Pietsch S, Mendil L, McPhail MJW, Johnson RS. Fitzpatrick SF, et al. Among authors: lambden s. Front Physiol. 2020 Mar 3;11:147. doi: 10.3389/fphys.2020.00147. eCollection 2020. Front Physiol. 2020. PMID: 32194434 Free PMC article.

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