Major M - Search Results

1

Modeling of patient virus titers suggests that availability of a vaccine could reduce hepatitis C virus transmission among injecting drug users.

Major M, Gutfraind A, Shekhtman L, Cui Q, Kachko A, Cotler SJ, Hajarizadeh B, Sacks-Davis R, Page K, Boodram B, Dahari H. Major M, et al. Sci Transl Med. 2018 Jul 11;10(449):eaao4496. doi: 10.1126/scitranslmed.aao4496. Sci Transl Med. 2018. PMID: 29997251 Free PMC article.

2

Hepatitis C virus kinetics and host responses associated with disease and outcome of infection in chimpanzees.

Major ME, Dahari H, Mihalik K, Puig M, Rice CM, Neumann AU, Feinstone SM. Major ME, et al. Hepatology. 2004 Jun;39(6):1709-20. doi: 10.1002/hep.20239. Hepatology. 2004. PMID: 15185313

3

Mathematical modeling of primary hepatitis C infection: noncytolytic clearance and early blockage of virion production.

Dahari H, Major M, Zhang X, Mihalik K, Rice CM, Perelson AS, Feinstone SM, Neumann AU. Dahari H, et al. Among authors: major m. Gastroenterology. 2005 Apr;128(4):1056-66. doi: 10.1053/j.gastro.2005.01.049. Gastroenterology. 2005. PMID: 15825086

4

CD4+ immune escape and subsequent T-cell failure following chimpanzee immunization against hepatitis C virus.

Puig M, Mihalik K, Tilton JC, Williams O, Merchlinsky M, Connors M, Feinstone SM, Major ME. Puig M, et al. Among authors: major me. Hepatology. 2006 Sep;44(3):736-45. doi: 10.1002/hep.21319. Hepatology. 2006. PMID: 16941702

5

Depletion of interfering antibodies in chronic hepatitis C patients and vaccinated chimpanzees reveals broad cross-genotype neutralizing activity.

Zhang P, Zhong L, Struble EB, Watanabe H, Kachko A, Mihalik K, Virata ML, Alter HJ, Feinstone S, Major M. Zhang P, et al. Among authors: major m. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7537-41. doi: 10.1073/pnas.0902749106. Epub 2009 Apr 20. Proc Natl Acad Sci U S A. 2009. PMID: 19380744 Free PMC article.

6

T-cell vaccines that elicit effective immune responses against HCV in chimpanzees may create greater immune pressure for viral mutation.

Zubkova I, Choi YH, Chang E, Pirollo K, Uren T, Watanabe H, Wells F, Kachko A, Krawczynski K, Major ME. Zubkova I, et al. Among authors: major me. Vaccine. 2009 Apr 28;27(19):2594-602. doi: 10.1016/j.vaccine.2009.02.045. Epub 2009 Feb 24. Vaccine. 2009. PMID: 19428866

7

Meta-analysis of hepatitis C virus vaccine efficacy in chimpanzees indicates an importance for structural proteins.

Dahari H, Feinstone SM, Major ME. Dahari H, et al. Among authors: major me. Gastroenterology. 2010 Sep;139(3):965-74. doi: 10.1053/j.gastro.2010.05.077. Epub 2010 Jun 2. Gastroenterology. 2010. PMID: 20621699 Free PMC article.

8

New neutralizing antibody epitopes in hepatitis C virus envelope glycoproteins are revealed by dissecting peptide recognition profiles.

Kachko A, Kochneva G, Sivolobova G, Grazhdantseva A, Lupan T, Zubkova I, Wells F, Merchlinsky M, Williams O, Watanabe H, Ivanova A, Shvalov A, Loktev V, Netesov S, Major ME. Kachko A, et al. Among authors: major me. Vaccine. 2011 Dec 9;30(1):69-77. doi: 10.1016/j.vaccine.2011.10.045. Epub 2011 Oct 29. Vaccine. 2011. PMID: 22041300

9

Prospects for prophylactic and therapeutic vaccines against hepatitis C virus.

Feinstone SM, Hu DJ, Major ME. Feinstone SM, et al. Among authors: major me. Clin Infect Dis. 2012 Jul;55 Suppl 1:S25-32. doi: 10.1093/cid/cis362. Clin Infect Dis. 2012. PMID: 22715210 Review.

10

Amino acid residue-specific neutralization and nonneutralization of hepatitis C virus by monoclonal antibodies to the E2 protein.

Duan H, Kachko A, Zhong L, Struble E, Pandey S, Yan H, Harman C, Virata-Theimer ML, Deng L, Zhao Z, Major M, Feinstone S, Zhang P. Duan H, et al. Among authors: major m. J Virol. 2012 Dec;86(23):12686-94. doi: 10.1128/JVI.00994-12. Epub 2012 Sep 12. J Virol. 2012. PMID: 22973024 Free PMC article.

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