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Inherited disorders of cobalamin metabolism disrupt nucleocytoplasmic transport of mRNA through impaired methylation/phosphorylation of ELAVL1/HuR.
Battaglia-Hsu SF, Ghemrawi R, Coelho D, Dreumont N, Mosca P, Hergalant S, Gauchotte G, Sequeira JM, Ndiongue M, Houlgatte R, Alberto JM, Umoret R, Robert A, Paoli J, Jung M, Quadros EV, Guéant JL. Battaglia-Hsu SF, et al. Among authors: jung m. Nucleic Acids Res. 2018 Sep 6;46(15):7844-7857. doi: 10.1093/nar/gky634. Nucleic Acids Res. 2018. PMID: 30016500 Free PMC article.
BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER.
Schäuble N, Lang S, Jung M, Cappel S, Schorr S, Ulucan Ö, Linxweiler J, Dudek J, Blum R, Helms V, Paton AW, Paton JC, Cavalié A, Zimmermann R. Schäuble N, et al. Among authors: jung m. EMBO J. 2012 Aug 1;31(15):3282-96. doi: 10.1038/emboj.2012.189. Epub 2012 Jul 13. EMBO J. 2012. PMID: 22796945 Free PMC article.
Targeting cell migration and the endoplasmic reticulum stress response with calmodulin antagonists: a clinically tested small molecule phenocopy of SEC62 gene silencing in human tumor cells.
Linxweiler M, Schorr S, Schäuble N, Jung M, Linxweiler J, Langer F, Schäfers HJ, Cavalié A, Zimmermann R, Greiner M. Linxweiler M, et al. Among authors: jung m. BMC Cancer. 2013 Dec 5;13:574. doi: 10.1186/1471-2407-13-574. BMC Cancer. 2013. PMID: 24304694 Free PMC article.
Evolutionary gain of function for the ER membrane protein Sec62 from yeast to humans.
Müller L, de Escauriaza MD, Lajoie P, Theis M, Jung M, Müller A, Burgard C, Greiner M, Snapp EL, Dudek J, Zimmermann R. Müller L, et al. Among authors: jung m. Mol Biol Cell. 2010 Mar 1;21(5):691-703. doi: 10.1091/mbc.e09-08-0730. Epub 2010 Jan 13. Mol Biol Cell. 2010. PMID: 20071467 Free PMC article.
Sec61 complexes form ubiquitous ER Ca2+ leak channels.
Lang S, Erdmann F, Jung M, Wagner R, Cavalie A, Zimmermann R. Lang S, et al. Among authors: jung m. Channels (Austin). 2011 May-Jun;5(3):228-35. doi: 10.4161/chan.5.3.15314. Epub 2011 May 1. Channels (Austin). 2011. PMID: 21406962 Free article.
Protein transport into the human endoplasmic reticulum.
Dudek J, Pfeffer S, Lee PH, Jung M, Cavalié A, Helms V, Förster F, Zimmermann R. Dudek J, et al. Among authors: jung m. J Mol Biol. 2015 Mar 27;427(6 Pt A):1159-75. doi: 10.1016/j.jmb.2014.06.011. Epub 2014 Jun 23. J Mol Biol. 2015. PMID: 24968227 Review.
5,553 results