Lai MJ - Search Results

1

5-Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer's Disease Phenotypes.

Lee HY, Fan SJ, Huang FI, Chao HY, Hsu KC, Lin TE, Yeh TK, Lai MJ, Li YH, Huang HL, Yang CR, Liou JP. Lee HY, et al. Among authors: lai mj. J Med Chem. 2018 Aug 23;61(16):7087-7102. doi: 10.1021/acs.jmedchem.8b00151. Epub 2018 Aug 9. J Med Chem. 2018. PMID: 30028616

2

Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents.

Reddy GR, Kuo CC, Tan UK, Coumar MS, Chang CY, Chiang YK, Lai MJ, Yeh JY, Wu SY, Chang JY, Liou JP, Hsieh HP. Reddy GR, et al. Among authors: lai mj. J Med Chem. 2008 Dec 25;51(24):8163-7. doi: 10.1021/jm8008635. J Med Chem. 2008. PMID: 19053773

3

Synthesis and structure-activity relationships of 1-benzyl-4,5,6-trimethoxyindoles as a novel class of potent antimitotic agents.

Lai MJ, Kuo CC, Yeh TK, Hsieh HP, Chen LT, Pan WY, Hsu KY, Chang JY, Liou JP. Lai MJ, et al. ChemMedChem. 2009 Apr;4(4):588-93. doi: 10.1002/cmdc.200800405. ChemMedChem. 2009. PMID: 19266513

4

2-amino-3,4,5-trimethoxybenzophenones as potent tubulin polymerization inhibitors.

Chuang HY, Chang JY, Lai MJ, Kuo CC, Lee HY, Hsieh HP, Chen YJ, Chen LT, Pan WY, Liou JP. Chuang HY, et al. Among authors: lai mj. ChemMedChem. 2011 Mar 7;6(3):450-6. doi: 10.1002/cmdc.201000479. Epub 2011 Jan 4. ChemMedChem. 2011. PMID: 21360819

5

Concise syntheses of N-aryl-5,6,7-trimethoxyindoles as antimitotic and vascular disrupting agents: application of the copper-mediated Ullmann-type arylation.

Lee HY, Chang JY, Chang LY, Lai WY, Lai MJ, Shih KH, Kuo CC, Chang CY, Liou JP. Lee HY, et al. Among authors: lai mj, lai wy. Org Biomol Chem. 2011 May 7;9(9):3154-7. doi: 10.1039/c0ob01038c. Epub 2011 Mar 17. Org Biomol Chem. 2011. PMID: 21416070

6

Synthesis and biological evaluation of 1-(4'-Indolyl and 6'-Quinolinyl) indoles as a new class of potent anticancer agents.

Lai MJ, Chang JY, Lee HY, Kuo CC, Lin MH, Hsieh HP, Chang CY, Wu JS, Wu SY, Shey KS, Liou JP. Lai MJ, et al. Eur J Med Chem. 2011 Sep;46(9):3623-9. doi: 10.1016/j.ejmech.2011.04.065. Epub 2011 May 20. Eur J Med Chem. 2011. PMID: 21641700

7

Synthesis and biological evaluation of 1-arylsulfonyl-5-(N-hydroxyacrylamide)indoles as potent histone deacetylase inhibitors with antitumor activity in vivo.

Lai MJ, Huang HL, Pan SL, Liu YM, Peng CY, Lee HY, Yeh TK, Huang PH, Teng CM, Chen CS, Chuang HY, Liou JP. Lai MJ, et al. J Med Chem. 2012 Apr 26;55(8):3777-91. doi: 10.1021/jm300197a. Epub 2012 Apr 5. J Med Chem. 2012. PMID: 22439863 Free PMC article.

8

Anticancer activity of MPT0E028, a novel potent histone deacetylase inhibitor, in human colorectal cancer HCT116 cells in vitro and in vivo.

Huang HL, Lee HY, Tsai AC, Peng CY, Lai MJ, Wang JC, Pan SL, Teng CM, Liou JP. Huang HL, et al. Among authors: lai mj. PLoS One. 2012;7(8):e43645. doi: 10.1371/journal.pone.0043645. Epub 2012 Aug 22. PLoS One. 2012. PMID: 22928010 Free PMC article.

9

1-arylsulfonyl-5-(N-hydroxyacrylamide)indolines histone deacetylase inhibitors are potent cytokine release suppressors.

Lee HY, Yang CR, Lai MJ, Huang HL, Hsieh YL, Liu YM, Yeh TK, Li YH, Mehndiratta S, Teng CM, Liou JP. Lee HY, et al. Among authors: lai mj. Chembiochem. 2013 Jul 8;14(10):1248-54. doi: 10.1002/cbic.201300201. Epub 2013 Jun 20. Chembiochem. 2013. PMID: 23788254

10

Furanylazaindoles: potent anticancer agents in vitro and in vivo.

Lee HY, Pan SL, Su MC, Liu YM, Kuo CC, Chang YT, Wu JS, Nien CY, Mehndiratta S, Chang CY, Wu SY, Lai MJ, Chang JY, Liou JP. Lee HY, et al. Among authors: lai mj. J Med Chem. 2013 Oct 24;56(20):8008-18. doi: 10.1021/jm4011115. Epub 2013 Oct 9. J Med Chem. 2013. PMID: 24106982

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