Yang CR - Search Results

1

5-Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer's Disease Phenotypes.

Lee HY, Fan SJ, Huang FI, Chao HY, Hsu KC, Lin TE, Yeh TK, Lai MJ, Li YH, Huang HL, Yang CR, Liou JP. Lee HY, et al. Among authors: yang cr. J Med Chem. 2018 Aug 23;61(16):7087-7102. doi: 10.1021/acs.jmedchem.8b00151. Epub 2018 Aug 9. J Med Chem. 2018. PMID: 30028616

2

Anti-arthritic effects of magnolol in human interleukin 1β-stimulated fibroblast-like synoviocytes and in a rat arthritis model.

Wang JH, Shih KS, Liou JP, Wu YW, Chang AS, Wang KL, Tsai CL, Yang CR. Wang JH, et al. Among authors: yang cr. PLoS One. 2012;7(2):e31368. doi: 10.1371/journal.pone.0031368. Epub 2012 Feb 16. PLoS One. 2012. PMID: 22359588 Free PMC article.

3

1-arylsulfonyl-5-(N-hydroxyacrylamide)indolines histone deacetylase inhibitors are potent cytokine release suppressors.

Lee HY, Yang CR, Lai MJ, Huang HL, Hsieh YL, Liu YM, Yeh TK, Li YH, Mehndiratta S, Teng CM, Liou JP. Lee HY, et al. Among authors: yang cr. Chembiochem. 2013 Jul 8;14(10):1248-54. doi: 10.1002/cbic.201300201. Epub 2013 Jun 20. Chembiochem. 2013. PMID: 23788254

4

Histone deacetylase inhibitors increase microRNA-146a expression and enhance negative regulation of interleukin-1β signaling in osteoarthritis fibroblast-like synoviocytes.

Wang JH, Shih KS, Wu YW, Wang AW, Yang CR. Wang JH, et al. Among authors: yang cr. Osteoarthritis Cartilage. 2013 Dec;21(12):1987-96. doi: 10.1016/j.joca.2013.09.008. Epub 2013 Oct 6. Osteoarthritis Cartilage. 2013. PMID: 24107356 Free article.

5

Denbinobin upregulates miR-146a expression and attenuates IL-1β-induced upregulation of ICAM-1 and VCAM-1 expressions in osteoarthritis fibroblast-like synoviocytes.

Yang CR, Shih KS, Liou JP, Wu YW, Hsieh IN, Lee HY, Lin TC, Wang JH. Yang CR, et al. J Mol Med (Berl). 2014 Nov;92(11):1147-58. doi: 10.1007/s00109-014-1192-8. Epub 2014 Jul 23. J Mol Med (Berl). 2014. PMID: 25052989

6

Indole-3-ethylsulfamoylphenylacrylamides: potent histone deacetylase inhibitors with anti-inflammatory activity.

Mehndiratta S, Hsieh YL, Liu YM, Wang AW, Lee HY, Liang LY, Kumar S, Teng CM, Yang CR, Liou JP. Mehndiratta S, et al. Among authors: yang cr. Eur J Med Chem. 2014 Oct 6;85:468-79. doi: 10.1016/j.ejmech.2014.08.020. Epub 2014 Aug 7. Eur J Med Chem. 2014. PMID: 25113875

7

Anticancer activity of MPT0G157, a derivative of indolylbenzenesulfonamide, inhibits tumor growth and angiogenesis.

Huang YC, Huang FI, Mehndiratta S, Lai SC, Liou JP, Yang CR. Huang YC, et al. Among authors: yang cr. Oncotarget. 2015 Jul 30;6(21):18590-601. doi: 10.18632/oncotarget.4068. Oncotarget. 2015. PMID: 26087180 Free PMC article.

8

Novel histone deacetylase inhibitor MPT0G009 induces cell apoptosis and synergistic anticancer activity with tumor necrosis factor-related apoptosis-inducing ligand against human hepatocellular carcinoma.

Chen MC, Huang HH, Lai CY, Lin YJ, Liou JP, Lai MJ, Li YH, Teng CM, Yang CR. Chen MC, et al. Among authors: yang cr. Oncotarget. 2016 Jan 5;7(1):402-17. doi: 10.18632/oncotarget.6352. Oncotarget. 2016. PMID: 26587975 Free PMC article.

9

2-(Phenylsulfonyl)quinoline N-hydroxyacrylamides as potent anticancer agents inhibiting histone deacetylase.

Lee HY, Chang CY, Su CJ, Huang HL, Mehndiratta S, Chao YH, Hsu CM, Kumar S, Sung TY, Huang YZ, Li YH, Yang CR, Liou JP. Lee HY, et al. Among authors: yang cr. Eur J Med Chem. 2016 Oct 21;122:92-101. doi: 10.1016/j.ejmech.2016.06.023. Epub 2016 Jun 16. Eur J Med Chem. 2016. PMID: 27344487

10

3-Aroylindoles display antitumor activity in vitro and in vivo: Effects of N1-substituents on biological activity.

Lee HY, Lee JF, Kumar S, Wu YW, HuangFu WC, Lai MJ, Li YH, Huang HL, Kuo FC, Hsiao CJ, Cheng CC, Yang CR, Liou JP. Lee HY, et al. Among authors: yang cr. Eur J Med Chem. 2017 Jan 5;125:1268-1278. doi: 10.1016/j.ejmech.2016.11.033. Epub 2016 Nov 15. Eur J Med Chem. 2017. PMID: 27886544

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