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The counterregulatory response to hypoglycaemia in the pig.
Gradel AKJ, Kildegaard J, Ludvigsen TP, Porsgaard T, Schou-Pedersen AMV, Fels JJ, Lykkesfeldt J, Refsgaard HHF. Gradel AKJ, et al. Among authors: porsgaard t. Basic Clin Pharmacol Toxicol. 2020 Oct;127(4):278-286. doi: 10.1111/bcpt.13422. Epub 2020 May 11. Basic Clin Pharmacol Toxicol. 2020. PMID: 32343047 Free article.
Molecular Engineering of Insulin Icodec, the First Acylated Insulin Analog for Once-Weekly Administration in Humans.
Kjeldsen TB, Hubálek F, Hjørringgaard CU, Tagmose TM, Nishimura E, Stidsen CE, Porsgaard T, Fledelius C, Refsgaard HHF, Gram-Nielsen S, Naver H, Pridal L, Hoeg-Jensen T, Jeppesen CB, Manfè V, Ludvigsen S, Lautrup-Larsen I, Madsen P. Kjeldsen TB, et al. Among authors: porsgaard t. J Med Chem. 2021 Jul 8;64(13):8942-8950. doi: 10.1021/acs.jmedchem.1c00257. Epub 2021 May 4. J Med Chem. 2021. PMID: 33944562 Free article.
Intraintestinal and Parenteral Administration of an Insulin Analogue Leads to Comparable Activation of Signaling Downstream of the Insulin Receptor in the Small Intestine.
Hvid H, Kildegaard J, Kristensen K, Porsgaard T, Jørgensen MS, Ballarín-González B, Ahnfelt-Rønne J, Hansen BF, Nishimura E. Hvid H, et al. Among authors: porsgaard t. J Diabetes Sci Technol. 2020 Jan;14(1):112-119. doi: 10.1177/1932296819855075. Epub 2019 Jun 12. J Diabetes Sci Technol. 2020. PMID: 31189343 Free PMC article.
Molecular engineering of safe and efficacious oral basal insulin.
Hubálek F, Refsgaard HHF, Gram-Nielsen S, Madsen P, Nishimura E, Münzel M, Brand CL, Stidsen CE, Claussen CH, Wulff EM, Pridal L, Ribel U, Kildegaard J, Porsgaard T, Johansson E, Steensgaard DB, Hovgaard L, Glendorf T, Hansen BF, Jensen MK, Nielsen PK, Ludvigsen S, Rugh S, Garibay PW, Moore MC, Cherrington AD, Kjeldsen T. Hubálek F, et al. Among authors: porsgaard t. Nat Commun. 2020 Jul 27;11(1):3746. doi: 10.1038/s41467-020-17487-9. Nat Commun. 2020. PMID: 32719315 Free PMC article.
33 results