Xu T - Search Results

1

Design, Synthesis, and Biological Evaluation of 3-(Imidazo[1,2- a]pyrazin-3-ylethynyl)-4-isopropyl- N-(3-((4-methylpiperazin-1-yl)methyl)-5-(trifluoromethyl)phenyl)benzamide as a Dual Inhibitor of Discoidin Domain Receptors 1 and 2.

Wang Z, Zhang Y, Pinkas DM, Fox AE, Luo J, Huang H, Cui S, Xiang Q, Xu T, Xun Q, Zhu D, Tu Z, Ren X, Brekken RA, Bullock AN, Liang G, Ding K, Lu X. Wang Z, et al. Among authors: xu t. J Med Chem. 2018 Sep 13;61(17):7977-7990. doi: 10.1021/acs.jmedchem.8b01045. Epub 2018 Aug 20. J Med Chem. 2018. PMID: 30075624 Free PMC article.

2

Tetrahydroisoquinoline-7-carboxamide Derivatives as New Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors.

Wang Z, Zhang Y, Bartual SG, Luo J, Xu T, Du W, Xun Q, Tu Z, Brekken RA, Ren X, Bullock AN, Liang G, Lu X, Ding K. Wang Z, et al. Among authors: xu t. ACS Med Chem Lett. 2017 Feb 9;8(3):327-332. doi: 10.1021/acsmedchemlett.6b00497. eCollection 2017 Mar 9. ACS Med Chem Lett. 2017. PMID: 28337325 Free PMC article.

3

1-Benzyl-4-phenyl-1H-1,2,3-triazoles improve the transcriptional functions of estrogen-related receptor γ and promote the browning of white adipose.

Xu S, Mao L, Ding P, Zhuang X, Zhou Y, Yu L, Liu Y, Nie T, Xu T, Xu Y, Liu J, Smaill J, Ren X, Wu D, Ding K. Xu S, et al. Among authors: xu t, xu y. Bioorg Med Chem. 2015 Jul 1;23(13):3751-60. doi: 10.1016/j.bmc.2015.03.082. Epub 2015 Apr 9. Bioorg Med Chem. 2015. PMID: 25910584

4

Design, Synthesis, and Structure-Activity Relationship Study of Novel Indole-2-carboxamide Derivatives as Anti-inflammatory Agents for the Treatment of Sepsis.

Liu Z, Tang L, Zhu H, Xu T, Qiu C, Zheng S, Gu Y, Feng J, Zhang Y, Liang G. Liu Z, et al. Among authors: xu t. J Med Chem. 2016 May 26;59(10):4637-50. doi: 10.1021/acs.jmedchem.5b02006. Epub 2016 May 11. J Med Chem. 2016. PMID: 27142640

5

Synthesis and optimization of novel allylated mono-carbonyl analogs of curcumin (MACs) act as potent anti-inflammatory agents against LPS-induced acute lung injury (ALI) in rats.

Zhu H, Xu T, Qiu C, Wu B, Zhang Y, Chen L, Xia Q, Li C, Zhou B, Liu Z, Liang G. Zhu H, et al. Among authors: xu t. Eur J Med Chem. 2016 Oct 4;121:181-193. doi: 10.1016/j.ejmech.2016.05.041. Epub 2016 May 21. Eur J Med Chem. 2016. PMID: 27240273

6

Development of resveratrol-curcumin hybrids as potential therapeutic agents for inflammatory lung diseases.

Pan J, Xu T, Xu F, Zhang Y, Liu Z, Chen W, Fu W, Dai Y, Zhao Y, Feng J, Liang G. Pan J, et al. Among authors: xu t, xu f. Eur J Med Chem. 2017 Jan 5;125:478-491. doi: 10.1016/j.ejmech.2016.09.033. Epub 2016 Sep 10. Eur J Med Chem. 2017. PMID: 27689730

7

Discovery of new MD2 inhibitor from chalcone derivatives with anti-inflammatory effects in LPS-induced acute lung injury.

Zhang Y, Wu J, Ying S, Chen G, Wu B, Xu T, Liu Z, Liu X, Huang L, Shan X, Dai Y, Liang G. Zhang Y, et al. Among authors: xu t. Sci Rep. 2016 Apr 27;6:25130. doi: 10.1038/srep25130. Sci Rep. 2016. PMID: 27118147 Free PMC article.

8

A novel imidazopyridine derivative, X22, attenuates sepsis-induced lung and liver injury by inhibiting the inflammatory response in vitro and in vivo.

Ge X, Feng Z, Xu T, Wu B, Chen H, Xu F, Fu L, Shan X, Dai Y, Zhang Y, Liang G. Ge X, et al. Among authors: xu t, xu f. Drug Des Devel Ther. 2016 Jun 30;10:1947-59. doi: 10.2147/DDDT.S101449. eCollection 2016. Drug Des Devel Ther. 2016. PMID: 27390516 Free PMC article.

9

Targeting myeloid differentiation protein 2 by the new chalcone L2H21 protects LPS-induced acute lung injury.

Zhang Y, Xu T, Wu B, Chen H, Pan Z, Huang Y, Mei L, Dai Y, Liu X, Shan X, Liang G. Zhang Y, et al. Among authors: xu t. J Cell Mol Med. 2017 Apr;21(4):746-757. doi: 10.1111/jcmm.13017. Epub 2016 Nov 18. J Cell Mol Med. 2017. PMID: 27860279 Free PMC article.

10

Inhibition of epidermal growth factor receptor attenuates LPS-induced inflammation and acute lung injury in rats.

Shan X, Zhang Y, Chen H, Dong L, Wu B, Xu T, Hu J, Liu Z, Wang W, Wu L, Feng Z, Liang G. Shan X, et al. Among authors: xu t. Oncotarget. 2017 Apr 18;8(16):26648-26661. doi: 10.18632/oncotarget.15790. Oncotarget. 2017. PMID: 28460454 Free PMC article.

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