Orkin SH - Search Results

1

Canonical PRC2 function is essential for mammary gland development and affects chromatin compaction in mammary organoids.

Michalak EM, Milevskiy MJG, Joyce RM, Dekkers JF, Jamieson PR, Pal B, Dawson CA, Hu Y, Orkin SH, Alexander WS, Lindeman GJ, Smyth GK, Visvader JE. Michalak EM, et al. Among authors: orkin sh. PLoS Biol. 2018 Aug 6;16(8):e2004986. doi: 10.1371/journal.pbio.2004986. eCollection 2018 Aug. PLoS Biol. 2018. PMID: 30080881 Free PMC article.

2

The C-terminal zinc finger of GATA-1 or GATA-2 is sufficient to induce megakaryocytic differentiation of an early myeloid cell line.

Visvader JE, Crossley M, Hill J, Orkin SH, Adams JM. Visvader JE, et al. Among authors: orkin sh. Mol Cell Biol. 1995 Feb;15(2):634-41. doi: 10.1128/MCB.15.2.634. Mol Cell Biol. 1995. PMID: 7823932 Free PMC article.

3

FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation.

Tsang AP, Visvader JE, Turner CA, Fujiwara Y, Yu C, Weiss MJ, Crossley M, Orkin SH. Tsang AP, et al. Among authors: orkin sh. Cell. 1997 Jul 11;90(1):109-19. doi: 10.1016/s0092-8674(00)80318-9. Cell. 1997. PMID: 9230307 Free article.

4

The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation.

Visvader JE, Mao X, Fujiwara Y, Hahm K, Orkin SH. Visvader JE, et al. Among authors: orkin sh. Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13707-12. doi: 10.1073/pnas.94.25.13707. Proc Natl Acad Sci U S A. 1997. PMID: 9391090 Free PMC article.

5

Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development.

Visvader JE, Fujiwara Y, Orkin SH. Visvader JE, et al. Among authors: orkin sh. Genes Dev. 1998 Feb 15;12(4):473-9. doi: 10.1101/gad.12.4.473. Genes Dev. 1998. PMID: 9472016 Free PMC article.

6

The TEL/ETV6 gene is required specifically for hematopoiesis in the bone marrow.

Wang LC, Swat W, Fujiwara Y, Davidson L, Visvader J, Kuo F, Alt FW, Gilliland DG, Golub TR, Orkin SH. Wang LC, et al. Among authors: orkin sh. Genes Dev. 1998 Aug 1;12(15):2392-402. doi: 10.1101/gad.12.15.2392. Genes Dev. 1998. PMID: 9694803 Free PMC article.

7

Intersections between blood cell development and leukemia genes.

Orkin SH, Porcher C, Fujiwara Y, Visvader J, Wang LC. Orkin SH, et al. Cancer Res. 1999 Apr 1;59(7 Suppl):1784s-1787s; discussion 1788s. Cancer Res. 1999. PMID: 10197597

8

Defective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1.

Hahm K, Sum EY, Fujiwara Y, Lindeman GJ, Visvader JE, Orkin SH. Hahm K, et al. Among authors: orkin sh. Mol Cell Biol. 2004 Mar;24(5):2074-82. doi: 10.1128/MCB.24.5.2074-2082.2004. Mol Cell Biol. 2004. PMID: 14966286 Free PMC article.

9

EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency.

Shen X, Liu Y, Hsu YJ, Fujiwara Y, Kim J, Mao X, Yuan GC, Orkin SH. Shen X, et al. Among authors: orkin sh. Mol Cell. 2008 Nov 21;32(4):491-502. doi: 10.1016/j.molcel.2008.10.016. Mol Cell. 2008. PMID: 19026780 Free PMC article.

10

Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells.

Shen X, Kim W, Fujiwara Y, Simon MD, Liu Y, Mysliwiec MR, Yuan GC, Lee Y, Orkin SH. Shen X, et al. Among authors: orkin sh. Cell. 2009 Dec 24;139(7):1303-14. doi: 10.1016/j.cell.2009.12.003. Cell. 2009. PMID: 20064376 Free PMC article.

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