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NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5.
Baker PJ, Boucher D, Bierschenk D, Tebartz C, Whitney PG, D'Silva DB, Tanzer MC, Monteleone M, Robertson AA, Cooper MA, Alvarez-Diaz S, Herold MJ, Bedoui S, Schroder K, Masters SL. Baker PJ, et al. Among authors: monteleone m. Eur J Immunol. 2015 Oct;45(10):2918-26. doi: 10.1002/eji.201545655. Epub 2015 Aug 24. Eur J Immunol. 2015. PMID: 26173988 Free article.
Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages.
Kapetanovic R, Bokil NJ, Achard ME, Ong CL, Peters KM, Stocks CJ, Phan MD, Monteleone M, Schroder K, Irvine KM, Saunders BM, Walker MJ, Stacey KJ, McEwan AG, Schembri MA, Sweet MJ. Kapetanovic R, et al. Among authors: monteleone m. FASEB J. 2016 May;30(5):1901-12. doi: 10.1096/fj.201500061. Epub 2016 Feb 2. FASEB J. 2016. PMID: 26839376
In summary, our study provides new insights at the cellular level into the well-documented effects of zinc in promoting host defense against infectious disease, as well as the complex host subversion strategies employed by S Typhimurium to combat this pathway.-Kapetanovic, R., Bo …
In summary, our study provides new insights at the cellular level into the well-documented effects of zinc in promoting host defense against …
Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity.
Boucher D, Monteleone M, Coll RC, Chen KW, Ross CM, Teo JL, Gomez GA, Holley CL, Bierschenk D, Stacey KJ, Yap AS, Bezbradica JS, Schroder K. Boucher D, et al. Among authors: monteleone m. J Exp Med. 2018 Mar 5;215(3):827-840. doi: 10.1084/jem.20172222. Epub 2018 Feb 6. J Exp Med. 2018. PMID: 29432122 Free PMC article.
Vincristine-induced peripheral neuropathy is driven by canonical NLRP3 activation and IL-1β release.
Starobova H, Monteleone M, Adolphe C, Batoon L, Sandrock CJ, Tay B, Deuis JR, Smith AV, Mueller A, Nadar EI, Lawrence GP, Mayor A, Tolson E, Levesque JP, Pettit AR, Wainwright BJ, Schroder K, Vetter I. Starobova H, et al. Among authors: monteleone m. J Exp Med. 2021 May 3;218(5):e20201452. doi: 10.1084/jem.20201452. J Exp Med. 2021. PMID: 33656514 Free PMC article.
173 results