Brik A - Search Results

1

Palladium prompted on-demand cysteine chemistry for the synthesis of challenging and uniquely modified proteins.

Jbara M, Laps S, Morgan M, Kamnesky G, Mann G, Wolberger C, Brik A. Jbara M, et al. Among authors: brik a. Nat Commun. 2018 Aug 8;9(1):3154. doi: 10.1038/s41467-018-05628-0. Nat Commun. 2018. PMID: 30089783 Free PMC article.

2

Modifying the vicinity of the isopeptide bond to reveal differential behavior of ubiquitin chains with interacting proteins: organic chemistry applied to synthetic proteins.

Haj-Yahya N, Haj-Yahya M, Castañeda CA, Spasser L, Hemantha HP, Jbara M, Penner M, Ciechanover A, Fushman D, Brik A. Haj-Yahya N, et al. Among authors: brik a. Angew Chem Int Ed Engl. 2013 Oct 11;52(42):11149-53. doi: 10.1002/anie.201306118. Epub 2013 Sep 4. Angew Chem Int Ed Engl. 2013. PMID: 24006204 Free PMC article.

3

Solid phase chemical ligation employing a rink amide linker for the synthesis of histone H2B protein.

Jbara M, Seenaiah M, Brik A. Jbara M, et al. Among authors: brik a. Chem Commun (Camb). 2014 Oct 25;50(83):12534-7. doi: 10.1039/c4cc06499b. Chem Commun (Camb). 2014. PMID: 25196573

4

KPC1-mediated ubiquitination and proteasomal processing of NF-κB1 p105 to p50 restricts tumor growth.

Kravtsova-Ivantsiv Y, Shomer I, Cohen-Kaplan V, Snijder B, Superti-Furga G, Gonen H, Sommer T, Ziv T, Admon A, Naroditsky I, Jbara M, Brik A, Pikarsky E, Kwon YT, Doweck I, Ciechanover A. Kravtsova-Ivantsiv Y, et al. Among authors: brik a. Cell. 2015 Apr 9;161(2):333-47. doi: 10.1016/j.cell.2015.03.001. Cell. 2015. PMID: 25860612 Free article.

5

Convergent versus sequential protein synthesis: the case of ubiquitinated and glycosylated H2B.

Seenaiah M, Jbara M, Mali SM, Brik A. Seenaiah M, et al. Among authors: brik a. Angew Chem Int Ed Engl. 2015 Oct 12;54(42):12374-8. doi: 10.1002/anie.201503309. Epub 2015 Jun 16. Angew Chem Int Ed Engl. 2015. PMID: 26079184

6

Pushing the Boundaries of Chemical Protein Synthesis: The Case of Ubiquitin Chains and Polyubiquitinated Peptides and Proteins.

Meledin R, Mali SM, Brik A. Meledin R, et al. Among authors: brik a. Chem Rec. 2016 Feb;16(1):509-19. doi: 10.1002/tcr.201500209. Epub 2015 Oct 19. Chem Rec. 2016. PMID: 26477936 Review.

7

Chemical Synthesis of Ubiquitin Chains.

Hemantha HP, Bondalapati S, Singh SK, Brik A. Hemantha HP, et al. Among authors: brik a. Curr Protoc Chem Biol. 2015 Dec 2;7(4):229-248. doi: 10.1002/9780470559277.ch150099. Curr Protoc Chem Biol. 2015. PMID: 26629614

8

Chemical and semisynthesis of modified histones.

Maity SK, Jbara M, Brik A. Maity SK, et al. Among authors: brik a. J Pept Sci. 2016 May;22(5):252-9. doi: 10.1002/psc.2848. Epub 2016 Jan 18. J Pept Sci. 2016. PMID: 26778211 Review.

9

Structural basis for histone H2B deubiquitination by the SAGA DUB module.

Morgan MT, Haj-Yahya M, Ringel AE, Bandi P, Brik A, Wolberger C. Morgan MT, et al. Among authors: brik a. Science. 2016 Feb 12;351(6274):725-8. doi: 10.1126/science.aac5681. Science. 2016. PMID: 26912860 Free PMC article.

10

Chemical Synthesis of Phosphorylated Histone H2A at Tyr57 Reveals Insight into the Inhibition Mode of the SAGA Deubiquitinating Module.

Jbara M, Maity SK, Morgan M, Wolberger C, Brik A. Jbara M, et al. Among authors: brik a. Angew Chem Int Ed Engl. 2016 Apr 11;55(16):4972-6. doi: 10.1002/anie.201600638. Epub 2016 Mar 9. Angew Chem Int Ed Engl. 2016. PMID: 26960207 Free PMC article.

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