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Trp53 haploinsufficiency modifies EGFR-driven peripheral nerve sheath tumorigenesis.
Rahrmann EP, Moriarity BS, Otto GM, Watson AL, Choi K, Collins MH, Wallace M, Webber BR, Forster CL, Rizzardi AE, Schmechel SC, Ratner N, Largaespada DA. Rahrmann EP, et al. Among authors: moriarity bs. Am J Pathol. 2014 Jul;184(7):2082-98. doi: 10.1016/j.ajpath.2014.04.006. Epub 2014 May 13. Am J Pathol. 2014. PMID: 24832557 Free PMC article.
Slit-Robo GTPase-Activating Protein 2 as a metastasis suppressor in osteosarcoma.
Marko TA, Shamsan GA, Edwards EN, Hazelton PE, Rathe SK, Cornax I, Overn PR, Varshney J, Diessner BJ, Moriarity BS, O'Sullivan MG, Odde DJ, Largaespada DA. Marko TA, et al. Among authors: moriarity bs. Sci Rep. 2016 Dec 14;6:39059. doi: 10.1038/srep39059. Sci Rep. 2016. PMID: 27966608 Free PMC article.
CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism.
Dorr CR, Remmel RP, Muthusamy A, Fisher J, Moriarity BS, Yasuda K, Wu B, Guan W, Schuetz EG, Oetting WS, Jacobson PA, Israni AK. Dorr CR, et al. Among authors: moriarity bs. Drug Metab Dispos. 2017 Aug;45(8):957-965. doi: 10.1124/dmd.117.076307. Epub 2017 May 22. Drug Metab Dispos. 2017. PMID: 28533324 Free PMC article.
Rapid generation of Col7a1-/- mouse model of recessive dystrophic epidermolysis bullosa and partial rescue via immunosuppressive dermal mesenchymal stem cells.
Webber BR, O'Connor KT, McElmurry RT, Durgin EN, Eide CR, Lees CJ, Riddle MJ, Mathews WE, Frank NY, Kluth MA, Ganss C, Moriarity BS, Frank MH, Osborn MJ, Tolar J. Webber BR, et al. Among authors: moriarity bs. Lab Invest. 2017 Oct;97(10):1218-1224. doi: 10.1038/labinvest.2017.85. Epub 2017 Sep 11. Lab Invest. 2017. PMID: 28892093 Free PMC article.
CRISPR/Cas9 library screening for drug target discovery.
Kurata M, Yamamoto K, Moriarity BS, Kitagawa M, Largaespada DA. Kurata M, et al. Among authors: moriarity bs. J Hum Genet. 2018 Feb;63(2):179-186. doi: 10.1038/s10038-017-0376-9. Epub 2017 Nov 20. J Hum Genet. 2018. PMID: 29158600 Review.
Highly multiplexed genome engineering using CRISPR/Cas9 gRNA arrays.
Kurata M, Wolf NK, Lahr WS, Weg MT, Kluesner MG, Lee S, Hui K, Shiraiwa M, Webber BR, Moriarity BS. Kurata M, et al. Among authors: moriarity bs. PLoS One. 2018 Sep 17;13(9):e0198714. doi: 10.1371/journal.pone.0198714. eCollection 2018. PLoS One. 2018. PMID: 30222773 Free PMC article.
91 results