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Page 1
Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing.
Parras A, Anta H, Santos-Galindo M, Swarup V, Elorza A, Nieto-González JL, Picó S, Hernández IH, Díaz-Hernández JI, Belloc E, Rodolosse A, Parikshak NN, Peñagarikano O, Fernández-Chacón R, Irimia M, Navarro P, Geschwind DH, Méndez R, Lucas JJ. Parras A, et al. Among authors: lucas jj. Nature. 2018 Aug;560(7719):441-446. doi: 10.1038/s41586-018-0423-5. Epub 2018 Aug 15. Nature. 2018. PMID: 30111840 Free PMC article.
Presynaptic dysfunction in Huntington's disease.
Rozas JL, Gómez-Sánchez L, Tomás-Zapico C, Lucas JJ, Fernández-Chacón R. Rozas JL, et al. Among authors: lucas jj. Biochem Soc Trans. 2010 Apr;38(2):488-92. doi: 10.1042/BST0380488. Biochem Soc Trans. 2010. PMID: 20298208 Review.
In vivo P2X7 inhibition reduces amyloid plaques in Alzheimer's disease through GSK3β and secretases.
Diaz-Hernandez JI, Gomez-Villafuertes R, León-Otegui M, Hontecillas-Prieto L, Del Puerto A, Trejo JL, Lucas JJ, Garrido JJ, Gualix J, Miras-Portugal MT, Diaz-Hernandez M. Diaz-Hernandez JI, et al. Among authors: lucas jj. Neurobiol Aging. 2012 Aug;33(8):1816-28. doi: 10.1016/j.neurobiolaging.2011.09.040. Epub 2011 Nov 1. Neurobiol Aging. 2012. PMID: 22048123
Huntington's disease is a four-repeat tauopathy with tau nuclear rods.
Fernández-Nogales M, Cabrera JR, Santos-Galindo M, Hoozemans JJ, Ferrer I, Rozemuller AJ, Hernández F, Avila J, Lucas JJ. Fernández-Nogales M, et al. Among authors: lucas jj. Nat Med. 2014 Aug;20(8):881-5. doi: 10.1038/nm.3617. Epub 2014 Jul 20. Nat Med. 2014. PMID: 25038828 Free article.
MAP2 Splicing is Altered in Huntington's Disease.
Cabrera JR, Lucas JJ. Cabrera JR, et al. Among authors: lucas jj. Brain Pathol. 2017 Mar;27(2):181-189. doi: 10.1111/bpa.12387. Epub 2016 Jul 7. Brain Pathol. 2017. PMID: 27098187 Free PMC article.
Tau-positive nuclear indentations in P301S tauopathy mice.
Fernández-Nogales M, Santos-Galindo M, Merchán-Rubira J, Hoozemans JJM, Rábano A, Ferrer I, Avila J, Hernández F, Lucas JJ. Fernández-Nogales M, et al. Among authors: lucas jj. Brain Pathol. 2017 May;27(3):314-322. doi: 10.1111/bpa.12407. Epub 2016 Aug 2. Brain Pathol. 2017. PMID: 27338164 Free PMC article.
Faulty splicing and cytoskeleton abnormalities in Huntington's disease.
Fernández-Nogales M, Santos-Galindo M, Hernández IH, Cabrera JR, Lucas JJ. Fernández-Nogales M, et al. Among authors: lucas jj. Brain Pathol. 2016 Nov;26(6):772-778. doi: 10.1111/bpa.12430. Brain Pathol. 2016. PMID: 27529534 Free PMC article. Review.
Regulation of proteasome activity by P2Y2 receptor underlies the neuroprotective effects of extracellular nucleotides.
de Diego-García L, Ramírez-Escudero M, Sebastián-Serrano Á, Diaz-Hernández JI, Pintor J, Lucas JJ, Díaz-Hernández M. de Diego-García L, et al. Among authors: lucas jj. Biochim Biophys Acta Mol Basis Dis. 2017 Jan;1863(1):43-51. doi: 10.1016/j.bbadis.2016.10.012. Epub 2016 Oct 18. Biochim Biophys Acta Mol Basis Dis. 2017. PMID: 27768902 Free article.
283 results