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Page 1
Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing.
Parras A, Anta H, Santos-Galindo M, Swarup V, Elorza A, Nieto-González JL, Picó S, Hernández IH, Díaz-Hernández JI, Belloc E, Rodolosse A, Parikshak NN, Peñagarikano O, Fernández-Chacón R, Irimia M, Navarro P, Geschwind DH, Méndez R, Lucas JJ. Parras A, et al. Among authors: pico s. Nature. 2018 Aug;560(7719):441-446. doi: 10.1038/s41586-018-0423-5. Epub 2018 Aug 15. Nature. 2018. PMID: 30111840 Free PMC article.
CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable SLC19A3 deficiency in Huntington's disease.
Picó S, Parras A, Santos-Galindo M, Pose-Utrilla J, Castro M, Fraga E, Hernández IH, Elorza A, Anta H, Wang N, Martí-Sánchez L, Belloc E, Garcia-Esparcia P, Garrido JJ, Ferrer I, Macías-García D, Mir P, Artuch R, Pérez B, Hernández F, Navarro P, López-Sendón JL, Iglesias T, Yang XW, Méndez R, Lucas JJ. Picó S, et al. Sci Transl Med. 2021 Sep 29;13(613):eabe7104. doi: 10.1126/scitranslmed.abe7104. Epub 2021 Sep 29. Sci Transl Med. 2021. PMID: 34586830 Free article.
Pathogenic Mis-splicing of CPEB4 in Schizophrenia.
Ollà I, Pardiñas AF, Parras A, Hernández IH, Santos-Galindo M, Picó S, Callado LF, Elorza A, Rodríguez-López C, Fernández-Miranda G, Belloc E, Walters JTR, O'Donovan MC, Méndez R, Toma C, Meana JJ, Owen MJ, Lucas JJ. Ollà I, et al. Among authors: pico s. Biol Psychiatry. 2023 Aug 15;94(4):341-351. doi: 10.1016/j.biopsych.2023.03.010. Epub 2023 Mar 22. Biol Psychiatry. 2023. PMID: 36958377 Free article.
In vivo reprogramming leads to premature death linked to hepatic and intestinal failure.
Parras A, Vílchez-Acosta A, Desdín-Micó G, Picó S, Mrabti C, Montenegro-Borbolla E, Maroun CY, Haghani A, Brooke R, Del Carmen Maza M, Rechsteiner C, Battiston F, Branchina C, Perez K, Horvath S, Bertelli C, Sempoux C, Ocampo A. Parras A, et al. Among authors: pico s. Nat Aging. 2023 Dec;3(12):1509-1520. doi: 10.1038/s43587-023-00528-5. Epub 2023 Nov 27. Nat Aging. 2023. PMID: 38012287
PAH deficient pathology in humanized c.1066-11G>A phenylketonuria mice.
Martínez-Pizarro A, Picó S, López-Márquez A, Rodriguez-López C, Montalvo E, Alvarez M, Castro M, Ramón-Maiques S, Pérez B, Lucas JJ, Richard E, Desviat LR. Martínez-Pizarro A, et al. Among authors: pico s. Hum Mol Genet. 2024 Jun 5;33(12):1074-1089. doi: 10.1093/hmg/ddae051. Hum Mol Genet. 2024. PMID: 38520741 Free PMC article.
Loss of H3K9 trimethylation leads to premature aging.
Mrabti C, Yang N, Desdín-Micó G, Alonso-Calleja A, Vílchez-Acosta A, Pico S, Parras A, Piao Y, Schoenfeldt L, Luo S, Haghani A, Brooke R, Del Carmen Maza M, Branchina C, Maroun CY, von Meyenn F, Naveiras O, Horvath S, Sen P, Ocampo A. Mrabti C, et al. Among authors: pico s. bioRxiv [Preprint]. 2024 Jul 24:2024.07.24.604929. doi: 10.1101/2024.07.24.604929. bioRxiv. 2024. PMID: 39091811 Free PMC article. Preprint.
Global hotspots for soil nature conservation.
Guerra CA, Berdugo M, Eldridge DJ, Eisenhauer N, Singh BK, Cui H, Abades S, Alfaro FD, Bamigboye AR, Bastida F, Blanco-Pastor JL, de Los Ríos A, Durán J, Grebenc T, Illán JG, Liu YR, Makhalanyane TP, Mamet S, Molina-Montenegro MA, Moreno JL, Mukherjee A, Nahberger TU, Peñaloza-Bojacá GF, Plaza C, Picó S, Verma JP, Rey A, Rodríguez A, Tedersoo L, Teixido AL, Torres-Díaz C, Trivedi P, Wang J, Wang L, Wang J, Zaady E, Zhou X, Zhou XQ, Delgado-Baquerizo M. Guerra CA, et al. Among authors: pico s. Nature. 2022 Oct;610(7933):693-698. doi: 10.1038/s41586-022-05292-x. Epub 2022 Oct 12. Nature. 2022. PMID: 36224389
19 results