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Tebipenem, the first oral carbapenem antibiotic.
Jain A, Utley L, Parr TR, Zabawa T, Pucci MJ. Jain A, et al. Expert Rev Anti Infect Ther. 2018 Jul;16(7):513-522. doi: 10.1080/14787210.2018.1496821. Epub 2018 Jul 27. Expert Rev Anti Infect Ther. 2018. PMID: 30014729 Review.
Resistance among urinary tract pathogens collected in Europe during 2018.
Critchley IA, Cotroneo N, Pucci MJ, Jain A, Mendes RE. Critchley IA, et al. Among authors: jain a. J Glob Antimicrob Resist. 2020 Dec;23:439-444. doi: 10.1016/j.jgar.2020.10.020. Epub 2020 Nov 16. J Glob Antimicrob Resist. 2020. PMID: 33212286 Free article.
In Vitro and In Vivo Characterization of Tebipenem (TBP), an Orally Active Carbapenem, against Biothreat Pathogens.
Clayton NP, Jain A, Halasohoris SA, Pysz LM, Lembirik S, Zumbrun SD, Kane CD, Hackett MJ, Pfefferle D, Smiley MA, Anderson MS, Heine H, Meister GT, Pucci MJ. Clayton NP, et al. Among authors: jain a. Antimicrob Agents Chemother. 2021 May 1;65(5):e02385-20. doi: 10.1128/AAC.02385-20. Epub 2021 Feb 16. Antimicrob Agents Chemother. 2021. PMID: 33593844 Free PMC article.
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection.
Eckburg PB, Muir L, Critchley IA, Walpole S, Kwak H, Phelan AM, Moore G, Jain A, Keutzer T, Dane A, Melnick D, Talley AK. Eckburg PB, et al. Among authors: jain a. N Engl J Med. 2022 Apr 7;386(14):1327-1338. doi: 10.1056/NEJMoa2105462. N Engl J Med. 2022. PMID: 35388666 Clinical Trial.
Randomized, Double-Blind, Placebo- and Positive-Controlled Crossover Study of the Effects of Tebipenem Pivoxil Hydrobromide on QT/QTc Intervals in Healthy Subjects.
Gupta VK, Maier G, Eckburg P, Morelli L, Lei Y, Jain A, Manyak E, Melnick D. Gupta VK, et al. Among authors: jain a. Antimicrob Agents Chemother. 2021 Jun 17;65(7):e0014521. doi: 10.1128/AAC.00145-21. Epub 2021 Jun 17. Antimicrob Agents Chemother. 2021. PMID: 33875429 Free PMC article. Clinical Trial.
9,121 results