Schreiber SL - Search Results

1

Synergistic Effects of Stereochemistry and Appendages on the Performance Diversity of a Collection of Synthetic Compounds.

Melillo B, Zoller J, Hua BK, Verho O, Borghs JC, Nelson SD Jr, Maetani M, Wawer MJ, Clemons PA, Schreiber SL. Melillo B, et al. Among authors: schreiber sl. J Am Chem Soc. 2018 Sep 19;140(37):11784-11790. doi: 10.1021/jacs.8b07319. Epub 2018 Sep 6. J Am Chem Soc. 2018. PMID: 30133283 Free PMC article.

2

Exploiting site-site interactions on solid support to generate dimeric molecules.

Blackwell HE, Clemons PA, Schreiber SL. Blackwell HE, et al. Among authors: schreiber sl. Org Lett. 2001 Apr 19;3(8):1185-8. doi: 10.1021/ol015647i. Org Lett. 2001. PMID: 11348190

3

Split--pool synthesis of 1,3-dioxanes leading to arrayed stock solutions of single compounds sufficient for multiple phenotypic and protein-binding assays.

Sternson SM, Louca JB, Wong JC, Schreiber SL. Sternson SM, et al. Among authors: schreiber sl. J Am Chem Soc. 2001 Feb 28;123(8):1740-7. doi: 10.1021/ja0036108. J Am Chem Soc. 2001. PMID: 11456775

4

A one-bead, one-stock solution approach to chemical genetics: part 2.

Clemons PA, Koehler AN, Wagner BK, Sprigings TG, Spring DR, King RW, Schreiber SL, Foley MA. Clemons PA, et al. Among authors: schreiber sl. Chem Biol. 2001 Dec;8(12):1183-95. doi: 10.1016/s1074-5521(01)00086-2. Chem Biol. 2001. PMID: 11755397

5

Diversity-oriented synthesis of biaryl-containing medium rings using a one bead/one stock solution platform.

Spring DR, Krishnan S, Blackwell HE, Schreiber SL. Spring DR, et al. Among authors: schreiber sl. J Am Chem Soc. 2002 Feb 20;124(7):1354-63. doi: 10.1021/ja017248o. J Am Chem Soc. 2002. PMID: 11841305

6

Synthesis of calcineurin-resistant derivatives of FK506 and selection of compensatory receptors.

Clemons PA, Gladstone BG, Seth A, Chao ED, Foley MA, Schreiber SL. Clemons PA, et al. Among authors: schreiber sl. Chem Biol. 2002 Jan;9(1):49-61. doi: 10.1016/s1074-5521(02)00085-6. Chem Biol. 2002. PMID: 11841938

7

Skeletal diversity via a branched pathway: efficient synthesis of 29 400 discrete, polycyclic compounds and their arraying into stock solutions.

Kwon O, Park SB, Schreiber SL. Kwon O, et al. Among authors: schreiber sl. J Am Chem Soc. 2002 Nov 13;124(45):13402-4. doi: 10.1021/ja028086e. J Am Chem Soc. 2002. PMID: 12418890

8

Structural biasing elements for in-cell histone deacetylase paralog selectivity.

Wong JC, Hong R, Schreiber SL. Wong JC, et al. Among authors: schreiber sl. J Am Chem Soc. 2003 May 14;125(19):5586-7. doi: 10.1021/ja0341440. J Am Chem Soc. 2003. PMID: 12733869

9

Discovery of an inhibitor of a transcription factor using small molecule microarrays and diversity-oriented synthesis.

Koehler AN, Shamji AF, Schreiber SL. Koehler AN, et al. Among authors: schreiber sl. J Am Chem Soc. 2003 Jul 16;125(28):8420-1. doi: 10.1021/ja0352698. J Am Chem Soc. 2003. PMID: 12848532

10

Catalytic asymmetric [3+2] cycloaddition of azomethine ylides. Development of a versatile stepwise, three-component reaction for diversity-oriented synthesis.

Chen C, Li X, Schreiber SL. Chen C, et al. Among authors: schreiber sl. J Am Chem Soc. 2003 Aug 27;125(34):10174-5. doi: 10.1021/ja036558z. J Am Chem Soc. 2003. PMID: 12926931

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