Kwan K - Search Results

1

Identification of ethyl pyruvate as a NLRP3 inflammasome inhibitor that preserves mitochondrial integrity.

Li S, Liang F, Kwan K, Tang Y, Wang X, Tang Y, Li J, Yang H, Chavan SS, Wang H, Andersson U, Lu B, Tracey KJ. Li S, et al. Among authors: kwan k. Mol Med. 2018 Mar 15;24(1):8. doi: 10.1186/s10020-018-0006-9. Mol Med. 2018. PMID: 30134814 Free PMC article.

2

α7 nicotinic acetylcholine receptor signaling inhibits inflammasome activation by preventing mitochondrial DNA release.

Lu B, Kwan K, Levine YA, Olofsson PS, Yang H, Li J, Joshi S, Wang H, Andersson U, Chavan SS, Tracey KJ. Lu B, et al. Among authors: kwan k. Mol Med. 2014 Aug 14;20(1):350-8. doi: 10.2119/molmed.2013.00117. Mol Med. 2014. PMID: 24849809 Free PMC article.

3

JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation.

Lu B, Antoine DJ, Kwan K, Lundbäck P, Wähämaa H, Schierbeck H, Robinson M, Van Zoelen MA, Yang H, Li J, Erlandsson-Harris H, Chavan SS, Wang H, Andersson U, Tracey KJ. Lu B, et al. Among authors: kwan k. Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3068-73. doi: 10.1073/pnas.1316925111. Epub 2014 Jan 27. Proc Natl Acad Sci U S A. 2014. PMID: 24469805 Free PMC article.

4

Galantamine Attenuates Type 1 Diabetes and Inhibits Anti-Insulin Antibodies in Nonobese Diabetic Mice.

Hanes WM, Olofsson PS, Kwan K, Hudson LK, Chavan SS, Pavlov VA, Tracey KJ. Hanes WM, et al. Among authors: kwan k. Mol Med. 2015 Nov;21(1):702-708. doi: 10.2119/molmed.2015.00142. Epub 2015 Aug 17. Mol Med. 2015. PMID: 26322849 Free PMC article.

5

The Protective Mechanism of Fluorofenidone in Renal Interstitial Inflammation and Fibrosis.

Tang Y, Zhang F, Huang L, Yuan Q, Qin J, Li B, Wang N, Xie Y, Wang L, Wang W, Kwan K, Peng Z, Hu G, Li J, Tao L. Tang Y, et al. Among authors: kwan k. Am J Med Sci. 2015 Sep;350(3):195-203. doi: 10.1097/MAJ.0000000000000501. Am J Med Sci. 2015. PMID: 26035627

6

Epigallocatechin-3-gallate inhibits IL-6 synthesis and suppresses transsignaling by enhancing soluble gp130 production.

Ahmed S, Marotte H, Kwan K, Ruth JH, Campbell PL, Rabquer BJ, Pakozdi A, Koch AE. Ahmed S, et al. Among authors: kwan k. Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14692-7. doi: 10.1073/pnas.0802675105. Epub 2008 Sep 16. Proc Natl Acad Sci U S A. 2008. PMID: 18796608 Free PMC article.

7

Down-regulation of myeloid cell leukemia 1 by epigallocatechin-3-gallate sensitizes rheumatoid arthritis synovial fibroblasts to tumor necrosis factor alpha-induced apoptosis.

Ahmed S, Silverman MD, Marotte H, Kwan K, Matuszczak N, Koch AE. Ahmed S, et al. Among authors: kwan k. Arthritis Rheum. 2009 May;60(5):1282-93. doi: 10.1002/art.24488. Arthritis Rheum. 2009. PMID: 19404960 Free PMC article.

8

KMT2A regulates the autophagy-GATA4 axis through METTL3-mediated m⁶A modification of ATG4a to promote NPCs senescence and IVDD progression.

Wu O, Jin Y, Zhang Z, Zhou H, Xu W, Chen L, Jones M, Kwan KYH, Gao J, Zhang K, Cheng X, Chen Q, Wang X, Li YM, Guo Z, Sun J, Chen Z, Wang B, Wang X, Shen S, Wu A. Wu O, et al. Among authors: kwan kyh. Bone Res. 2024 Nov 21;12(1):67. doi: 10.1038/s41413-024-00373-1. Bone Res. 2024. PMID: 39572532 Free PMC article.

9

N6-Methyladenosine modification activates the serine synthesis pathway to mediate therapeutic resistance in liver cancer.

Chan FF, Kwan KK, Seoung DH, Chin DW, Ng IO, Wong CC, Wong CM. Chan FF, et al. Among authors: kwan kk. Mol Ther. 2024 Oct 26:S1525-0016(24)00685-3. doi: 10.1016/j.ymthe.2024.10.025. Online ahead of print. Mol Ther. 2024. PMID: 39489921

10

Role of oxidative stress in mitochondrial dysfunction and their implications in intervertebral disc degeneration: Mechanisms and therapeutic strategies.

Zhou H, Wu C, Jin Y, Wu O, Chen L, Guo Z, Wang X, Chen Q, Kwan KYH, Li YM, Xia D, Chen T, Wu A. Zhou H, et al. Among authors: kwan kyh. J Orthop Translat. 2024 Oct 16;49:181-206. doi: 10.1016/j.jot.2024.08.016. eCollection 2024 Nov. J Orthop Translat. 2024. PMID: 39483126 Free PMC article. Review.

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