Ko C - Search Results

1

Hepatitis B virus genome recycling and de novo secondary infection events maintain stable cccDNA levels.

Ko C, Chakraborty A, Chou WM, Hasreiter J, Wettengel JM, Stadler D, Bester R, Asen T, Zhang K, Wisskirchen K, McKeating JA, Ryu WS, Protzer U. Ko C, et al. J Hepatol. 2018 Dec;69(6):1231-1241. doi: 10.1016/j.jhep.2018.08.012. Epub 2018 Aug 22. J Hepatol. 2018. PMID: 30142426 Free PMC article.

2

Hydrophobic residues of terminal protein domain of hepatitis B virus polymerase contribute to distinct steps in viral genome replication.

Shin YC, Ko C, Ryu WS. Shin YC, et al. Among authors: ko c. FEBS Lett. 2011 Dec 15;585(24):3964-8. doi: 10.1016/j.febslet.2011.11.003. Epub 2011 Nov 10. FEBS Lett. 2011. PMID: 22079666 Free article.

3

Residues Arg703, Asp777, and Arg781 of the RNase H domain of hepatitis B virus polymerase are critical for viral DNA synthesis.

Ko C, Shin YC, Park WJ, Kim S, Kim J, Ryu WS. Ko C, et al. J Virol. 2014 Jan;88(1):154-63. doi: 10.1128/JVI.01916-13. Epub 2013 Oct 16. J Virol. 2014. PMID: 24131721 Free PMC article.

4

DDX3 DEAD-box RNA helicase is a host factor that restricts hepatitis B virus replication at the transcriptional level.

Ko C, Lee S, Windisch MP, Ryu WS. Ko C, et al. J Virol. 2014 Dec;88(23):13689-98. doi: 10.1128/JVI.02035-14. Epub 2014 Sep 17. J Virol. 2014. PMID: 25231298 Free PMC article.

5

The FDA-approved drug irbesartan inhibits HBV-infection in HepG2 cells stably expressing sodium taurocholate co-transporting polypeptide.

Ko C, Park WJ, Park S, Kim S, Windisch MP, Ryu WS. Ko C, et al. Antivir Ther. 2015;20(8):835-42. doi: 10.3851/IMP2965. Epub 2015 May 1. Antivir Ther. 2015. PMID: 25929767

6

Blocking sense-strand activity improves potency, safety and specificity of anti-hepatitis B virus short hairpin RNA.

Michler T, Große S, Mockenhaupt S, Röder N, Stückler F, Knapp B, Ko C, Heikenwalder M, Protzer U, Grimm D. Michler T, et al. Among authors: ko c. EMBO Mol Med. 2016 Sep 1;8(9):1082-98. doi: 10.15252/emmm.201506172. Print 2016 Sep. EMBO Mol Med. 2016. PMID: 27473329 Free PMC article.

7

DDB1 Stimulates Viral Transcription of Hepatitis B Virus via HBx-Independent Mechanisms.

Kim W, Lee S, Son Y, Ko C, Ryu WS. Kim W, et al. Among authors: ko c. J Virol. 2016 Oct 14;90(21):9644-9653. doi: 10.1128/JVI.00977-16. Print 2016 Nov 1. J Virol. 2016. PMID: 27535046 Free PMC article.

8

Analyses of HBV cccDNA Quantification and Modification.

Xia Y, Stadler D, Ko C, Protzer U. Xia Y, et al. Among authors: ko c. Methods Mol Biol. 2017;1540:59-72. doi: 10.1007/978-1-4939-6700-1_6. Methods Mol Biol. 2017. PMID: 27975308

9

Novel viral and host targets to cure hepatitis B.

Ko C, Michler T, Protzer U. Ko C, et al. Curr Opin Virol. 2017 Jun;24:38-45. doi: 10.1016/j.coviro.2017.03.019. Epub 2017 Apr 20. Curr Opin Virol. 2017. PMID: 28433762 Review.

10

Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques.

Burwitz BJ, Wettengel JM, Mück-Häusl MA, Ringelhan M, Ko C, Festag MM, Hammond KB, Northrup M, Bimber BN, Jacob T, Reed JS, Norris R, Park B, Moller-Tank S, Esser K, Greene JM, Wu HL, Abdulhaqq S, Webb G, Sutton WF, Klug A, Swanson T, Legasse AW, Vu TQ, Asokan A, Haigwood NL, Protzer U, Sacha JB. Burwitz BJ, et al. Among authors: ko c. Nat Commun. 2017 Dec 15;8(1):2146. doi: 10.1038/s41467-017-01953-y. Nat Commun. 2017. PMID: 29247188 Free PMC article.

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