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Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference-based bone anabolic strategy.
Liang C, Guo B, Wu H, Shao N, Li D, Liu J, Dang L, Wang C, Li H, Li S, Lau WK, Cao Y, Yang Z, Lu C, He X, Au DW, Pan X, Zhang BT, Lu C, Zhang H, Yue K, Qian A, Shang P, Xu J, Xiao L, Bian Z, Tan W, Liang Z, He F, Zhang L, Lu A, Zhang G. Liang C, et al. Nat Med. 2015 Mar;21(3):288-94. doi: 10.1038/nm.3791. Epub 2015 Feb 9. Nat Med. 2015. PMID: 25665179 Free PMC article.
Tumor cell-targeted delivery of CRISPR/Cas9 by aptamer-functionalized lipopolymer for therapeutic genome editing of VEGFA in osteosarcoma.
Liang C, Li F, Wang L, Zhang ZK, Wang C, He B, Li J, Chen Z, Shaikh AB, Liu J, Wu X, Peng S, Dang L, Guo B, He X, Au DWT, Lu C, Zhu H, Zhang BT, Lu A, Zhang G. Liang C, et al. Among authors: au dwt. Biomaterials. 2017 Dec;147:68-85. doi: 10.1016/j.biomaterials.2017.09.015. Epub 2017 Sep 13. Biomaterials. 2017. PMID: 28938163
A delivery system specifically approaching bone resorption surfaces to facilitate therapeutic modulation of microRNAs in osteoclasts.
Liu J, Dang L, Li D, Liang C, He X, Wu H, Qian A, Yang Z, Au DW, Chiang MW, Zhang BT, Han Q, Yue KK, Zhang H, Lv C, Pan X, Xu J, Bian Z, Shang P, Tan W, Liang Z, Guo B, Lu A, Zhang G. Liu J, et al. Biomaterials. 2015 Jun;52:148-60. doi: 10.1016/j.biomaterials.2015.02.007. Epub 2015 Feb 24. Biomaterials. 2015. PMID: 25818421
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