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Rationale and Design of the STOP-OB Study for Evaluating the Effects of Tofogliflozin and Glimepiride on Fat Deposition in Type 2 Diabetes Patients Treated with Metformin/DPP-4 Inhibitor Dual Therapy.
Ishihara H, Anai M, Seino H, Kitazawa T, Ohashi H, Ai M, Inoue M, Fujishiro M, Inazawa T, Kuroda H, Yamada M. Ishihara H, et al. Diabetes Ther. 2018 Oct;9(5):2117-2125. doi: 10.1007/s13300-018-0491-4. Epub 2018 Aug 25. Diabetes Ther. 2018. PMID: 30145651 Free PMC article.
DPP-IV inhibitor anagliptin exerts anti-inflammatory effects on macrophages, adipocytes, and mouse livers by suppressing NF-κB activation.
Shinjo T, Nakatsu Y, Iwashita M, Sano T, Sakoda H, Ishihara H, Kushiyama A, Fujishiro M, Fukushima T, Tsuchiya Y, Kamata H, Nishimura F, Asano T. Shinjo T, et al. Among authors: ishihara h. Am J Physiol Endocrinol Metab. 2015 Aug 1;309(3):E214-23. doi: 10.1152/ajpendo.00553.2014. Epub 2015 May 26. Am J Physiol Endocrinol Metab. 2015. PMID: 26015438 Free article.
Controversy regarding gastric cancer and diabetes.
Fujishiro M, Ishihara H. Fujishiro M, et al. Among authors: ishihara h. J Gastroenterol. 2016 Jan;51(1):80-1. doi: 10.1007/s00535-015-1113-9. Epub 2015 Aug 29. J Gastroenterol. 2016. PMID: 26318727 No abstract available.
The prolyl isomerase Pin1 increases β-cell proliferation and enhances insulin secretion.
Nakatsu Y, Mori K, Matsunaga Y, Yamamotoya T, Ueda K, Inoue Y, Mitsuzaki-Miyoshi K, Sakoda H, Fujishiro M, Yamaguchi S, Kushiyama A, Ono H, Ishihara H, Asano T. Nakatsu Y, et al. Among authors: ishihara h. J Biol Chem. 2017 Jul 14;292(28):11886-11895. doi: 10.1074/jbc.M117.780726. Epub 2017 May 31. J Biol Chem. 2017. PMID: 28566287 Free PMC article.
Elsberg syndrome related to varicella zoster virus infection with painless skin lesions in an elderly woman with poorly controlled type 2 diabetes mellitus.
Saito H, Ebashi M, Kushimoto M, Ikeda J, Egashira F, Yamaguchi S, Watanabe K, Ogawa K, Suzuki Y, Ishihara H, Fujishiro M. Saito H, et al. Among authors: ishihara h. Ther Clin Risk Manag. 2018 Oct 9;14:1951-1954. doi: 10.2147/TCRM.S178782. eCollection 2018. Ther Clin Risk Manag. 2018. PMID: 30349274 Free PMC article.
Prolyl Isomerase Pin1 Suppresses Thermogenic Programs in Adipocytes by Promoting Degradation of Transcriptional Co-activator PRDM16.
Nakatsu Y, Matsunaga Y, Yamamotoya T, Ueda K, Inoue MK, Mizuno Y, Nakanishi M, Sano T, Yamawaki Y, Kushiyama A, Sakoda H, Fujishiro M, Ryo A, Ono H, Minamino T, Takahashi SI, Ohno H, Yoneda M, Takahashi K, Ishihara H, Katagiri H, Nishimura F, Kanematsu T, Yamada T, Asano T. Nakatsu Y, et al. Among authors: ishihara h. Cell Rep. 2019 Mar 19;26(12):3221-3230.e3. doi: 10.1016/j.celrep.2019.02.066. Cell Rep. 2019. PMID: 30893596 Free article.
1,525 results