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Early postnatal behavioral, cellular, and molecular changes in models of Huntington disease are reversible by HDAC inhibition.
Siebzehnrübl FA, Raber KA, Urbach YK, Schulze-Krebs A, Canneva F, Moceri S, Habermeyer J, Achoui D, Gupta B, Steindler DA, Stephan M, Nguyen HP, Bonin M, Riess O, Bauer A, Aigner L, Couillard-Despres S, Paucar MA, Svenningsson P, Osmand A, Andreew A, Zabel C, Weiss A, Kuhn R, Moussaoui S, Blockx I, Van der Linden A, Cheong RY, Roybon L, Petersén Å, von Hörsten S. Siebzehnrübl FA, et al. Among authors: raber ka. Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8765-E8774. doi: 10.1073/pnas.1807962115. Epub 2018 Aug 27. Proc Natl Acad Sci U S A. 2018. PMID: 30150378 Free PMC article.
Sex differences in a transgenic rat model of Huntington's disease: decreased 17beta-estradiol levels correlate with reduced numbers of DARPP32+ neurons in males.
Bode FJ, Stephan M, Suhling H, Pabst R, Straub RH, Raber KA, Bonin M, Nguyen HP, Riess O, Bauer A, Sjoberg C, Petersén A, von Hörsten S. Bode FJ, et al. Among authors: raber ka. Hum Mol Genet. 2008 Sep 1;17(17):2595-609. doi: 10.1093/hmg/ddn159. Epub 2008 May 23. Hum Mol Genet. 2008. PMID: 18502785
Stem cell quiescence in the hippocampal neurogenic niche is associated with elevated transforming growth factor-beta signaling in an animal model of Huntington disease.
Kandasamy M, Couillard-Despres S, Raber KA, Stephan M, Lehner B, Winner B, Kohl Z, Rivera FJ, Nguyen HP, Riess O, Bogdahn U, Winkler J, von Hörsten S, Aigner L. Kandasamy M, et al. Among authors: raber ka. J Neuropathol Exp Neurol. 2010 Jul;69(7):717-28. doi: 10.1097/NEN.0b013e3181e4f733. J Neuropathol Exp Neurol. 2010. PMID: 20535034
Early Alterations in Operant Performance and Prominent Huntingtin Aggregation in a Congenic F344 Rat Line of the Classical CAGn51trunc Model of Huntington Disease.
Plank AC, Canneva F, Raber KA, Urbach YK, Dobner J, Puchades M, Bjaalie JG, Gillmann C, Bäuerle T, Riess O, Nguyen HHP, von Hörsten S. Plank AC, et al. Among authors: raber ka. Front Neurosci. 2018 Jan 25;12:11. doi: 10.3389/fnins.2018.00011. eCollection 2018. Front Neurosci. 2018. PMID: 29422836 Free PMC article.
Genotype specific age related changes in a transgenic rat model of Huntington's disease.
Blockx I, Van Camp N, Verhoye M, Boisgard R, Dubois A, Jego B, Jonckers E, Raber K, Siquier K, Kuhnast B, Dollé F, Nguyen HP, Von Hörsten S, Tavitian B, Van der Linden A. Blockx I, et al. Neuroimage. 2011 Oct 15;58(4):1006-16. doi: 10.1016/j.neuroimage.2011.07.007. Epub 2011 Jul 13. Neuroimage. 2011. PMID: 21767653
Selective striatal neuron loss and alterations in behavior correlate with impaired striatal function in Huntington's disease transgenic rats.
Kántor O, Temel Y, Holzmann C, Raber K, Nguyen HP, Cao C, Türkoglu HO, Rutten BP, Visser-Vandewalle V, Steinbusch HW, Blokland A, Korr H, Riess O, von Hörsten S, Schmitz C. Kántor O, et al. Neurobiol Dis. 2006 Jun;22(3):538-47. doi: 10.1016/j.nbd.2005.12.014. Epub 2006 Feb 9. Neurobiol Dis. 2006. PMID: 16480885
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