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31,103 results

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Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: a phase 1/2 trial.
Kennedy GA, Varelias A, Vuckovic S, Le Texier L, Gartlan KH, Zhang P, Thomas G, Anderson L, Boyle G, Cloonan N, Leach J, Sturgeon E, Avery J, Olver SD, Lor M, Misra AK, Hutchins C, Morton AJ, Durrant ST, Subramoniapillai E, Butler JP, Curley CI, MacDonald KPA, Tey SK, Hill GR. Kennedy GA, et al. Among authors: zhang p. Lancet Oncol. 2014 Dec;15(13):1451-1459. doi: 10.1016/S1470-2045(14)71017-4. Epub 2014 Nov 14. Lancet Oncol. 2014. PMID: 25456364 Clinical Trial.
Donor colonic CD103+ dendritic cells determine the severity of acute graft-versus-host disease.
Koyama M, Cheong M, Markey KA, Gartlan KH, Kuns RD, Locke KR, Lineburg KE, Teal BE, Leveque-El Mouttie L, Bunting MD, Vuckovic S, Zhang P, Teng MW, Varelias A, Tey SK, Wockner LF, Engwerda CR, Smyth MJ, Belz GT, McColl SR, MacDonald KP, Hill GR. Koyama M, et al. Among authors: zhang p. J Exp Med. 2015 Jul 27;212(8):1303-21. doi: 10.1084/jem.20150329. Epub 2015 Jul 13. J Exp Med. 2015. PMID: 26169940 Free PMC article.
Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome.
Varelias A, Ormerod KL, Bunting MD, Koyama M, Gartlan KH, Kuns RD, Lachner N, Locke KR, Lim CY, Henden AS, Zhang P, Clouston AD, Hasnain SZ, McGuckin MA, Blazar BR, MacDonald KP, Hugenholtz P, Hill GR. Varelias A, et al. Among authors: zhang p. Blood. 2017 Apr 13;129(15):2172-2185. doi: 10.1182/blood-2016-08-732628. Epub 2017 Jan 30. Blood. 2017. PMID: 28137828 Free PMC article.
Eomesodermin promotes the development of type 1 regulatory T (TR1) cells.
Zhang P, Lee JS, Gartlan KH, Schuster IS, Comerford I, Varelias A, Ullah MA, Vuckovic S, Koyama M, Kuns RD, Locke KR, Beckett KJ, Olver SD, Samson LD, Montes de Oca M, de Labastida Rivera F, Clouston AD, Belz GT, Blazar BR, MacDonald KP, McColl SR, Thomas R, Engwerda CR, Degli-Esposti MA, Kallies A, Tey SK, Hill GR. Zhang P, et al. Sci Immunol. 2017 Apr 7;2(10):eaah7152. doi: 10.1126/sciimmunol.aah7152. Sci Immunol. 2017. PMID: 28738016 Free PMC article.
Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion.
Lynch JP, Werder RB, Loh Z, Sikder MAA, Curren B, Zhang V, Rogers MJ, Lane K, Simpson J, Mazzone SB, Spann K, Hayball J, Diener K, Everard ML, Blyth CC, Forstner C, Dennis PG, Murtaza N, Morrison M, Ó Cuív P, Zhang P, Haque A, Hill GR, Sly PD, Upham JW, Phipps S. Lynch JP, et al. Among authors: zhang p, zhang v. J Exp Med. 2018 Feb 5;215(2):537-557. doi: 10.1084/jem.20170298. Epub 2017 Dec 22. J Exp Med. 2018. PMID: 29273643 Free PMC article.
Bone marrow transplantation generates T cell-dependent control of myeloma in mice.
Vuckovic S, Minnie SA, Smith D, Gartlan KH, Watkins TS, Markey KA, Mukhopadhyay P, Guillerey C, Kuns RD, Locke KR, Pritchard AL, Johansson PA, Varelias A, Zhang P, Huntington ND, Waddell N, Chesi M, Miles JJ, Smyth MJ, Hill GR. Vuckovic S, et al. Among authors: zhang p. J Clin Invest. 2019 Jan 2;129(1):106-121. doi: 10.1172/JCI98888. Epub 2018 Nov 19. J Clin Invest. 2019. PMID: 30300141 Free PMC article.
Phase I Trial of Inducible Caspase 9 T Cells in Adult Stem Cell Transplant Demonstrates Massive Clonotypic Proliferative Potential and Long-term Persistence of Transgenic T Cells.
Zhang P, Raju J, Ullah MA, Au R, Varelias A, Gartlan KH, Olver SD, Samson LD, Sturgeon E, Zomerdijk N, Avery J, Gargett T, Brown MP, Coin LJ, Ganesamoorthy D, Hutchins C, Pratt GR, Kennedy GA, Morton AJ, Curley CI, Hill GR, Tey SK. Zhang P, et al. Clin Cancer Res. 2019 Mar 15;25(6):1749-1755. doi: 10.1158/1078-0432.CCR-18-3069. Epub 2019 Feb 14. Clin Cancer Res. 2019. PMID: 30765390 Clinical Trial.
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