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Engineered CRISPR-Cas9 nuclease with expanded targeting space.
Nishimasu H, Shi X, Ishiguro S, Gao L, Hirano S, Okazaki S, Noda T, Abudayyeh OO, Gootenberg JS, Mori H, Oura S, Holmes B, Tanaka M, Seki M, Hirano H, Aburatani H, Ishitani R, Ikawa M, Yachie N, Zhang F, Nureki O. Nishimasu H, et al. Among authors: nureki o. Science. 2018 Sep 21;361(6408):1259-1262. doi: 10.1126/science.aas9129. Epub 2018 Aug 30. Science. 2018. PMID: 30166441 Free PMC article.
Crystal structure of archaeosine tRNA-guanine transglycosylase.
Ishitani R, Nureki O, Fukai S, Kijimoto T, Nameki N, Watanabe M, Kondo H, Sekine M, Okada N, Nishimura S, Yokoyama S. Ishitani R, et al. Among authors: nureki o. J Mol Biol. 2002 May 3;318(3):665-77. doi: 10.1016/S0022-2836(02)00090-6. J Mol Biol. 2002. PMID: 12054814
An enzyme with a deep trefoil knot for the active-site architecture.
Nureki O, Shirouzu M, Hashimoto K, Ishitani R, Terada T, Tamakoshi M, Oshima T, Chijimatsu M, Takio K, Vassylyev DG, Shibata T, Inoue Y, Kuramitsu S, Yokoyama S. Nureki O, et al. Acta Crystallogr D Biol Crystallogr. 2002 Jul;58(Pt 7):1129-37. doi: 10.1107/s0907444902006601. Epub 2002 Jun 20. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 12077432
383 results