Papo N - Search Results

1

Depsipeptides Featuring a Neutral P1 Are Potent Inhibitors of Kallikrein-Related Peptidase 6 with On-Target Cellular Activity.

De Vita E, Schüler P, Lovell S, Lohbeck J, Kullmann S, Rabinovich E, Sananes A, Heßling B, Hamon V, Papo N, Hess J, Tate EW, Gunkel N, Miller AK. De Vita E, et al. Among authors: papo n. J Med Chem. 2018 Oct 11;61(19):8859-8874. doi: 10.1021/acs.jmedchem.8b01106. Epub 2018 Sep 28. J Med Chem. 2018. PMID: 30212625

2

Identifying Residues that Determine SCF Molecular-Level Interactions through a Combination of Experimental and In silico Analyses.

Rabinovich E, Heyne M, Bakhman A, Kosloff M, Shifman JM, Papo N. Rabinovich E, et al. Among authors: papo n. J Mol Biol. 2017 Jan 6;429(1):97-114. doi: 10.1016/j.jmb.2016.11.018. Epub 2016 Nov 25. J Mol Biol. 2017. PMID: 27890784

3

A potent, proteolysis-resistant inhibitor of kallikrein-related peptidase 6 (KLK6) for cancer therapy, developed by combinatorial engineering.

Sananes A, Cohen I, Shahar A, Hockla A, De Vita E, Miller AK, Radisky ES, Papo N. Sananes A, et al. Among authors: papo n. J Biol Chem. 2018 Aug 17;293(33):12663-12680. doi: 10.1074/jbc.RA117.000871. Epub 2018 Jun 22. J Biol Chem. 2018. PMID: 29934309 Free PMC article.

4

Targeting the MMP-14/MMP-2/integrin α_vβ₃ axis with multispecific N-TIMP2-based antagonists for cancer therapy.

Yosef G, Arkadash V, Papo N. Yosef G, et al. Among authors: papo n. J Biol Chem. 2018 Aug 24;293(34):13310-13326. doi: 10.1074/jbc.RA118.004406. Epub 2018 Jul 9. J Biol Chem. 2018. PMID: 29986882 Free PMC article.

5

Residue-level determinants of angiopoietin-2 interactions with its receptor Tie2.

Bakhman A, Rabinovich E, Shlamkovich T, Papo N, Kosloff M. Bakhman A, et al. Among authors: papo n. Proteins. 2019 Mar;87(3):185-197. doi: 10.1002/prot.25638. Epub 2018 Dec 21. Proteins. 2019. PMID: 30520519

6

PRSS3/Mesotrypsin and kallikrein-related peptidase 5 are associated with poor prognosis and contribute to tumor cell invasion and growth in lung adenocarcinoma.

Ma H, Hockla A, Mehner C, Coban M, Papo N, Radisky DC, Radisky ES. Ma H, et al. Among authors: papo n. Sci Rep. 2019 Feb 12;9(1):1844. doi: 10.1038/s41598-018-38362-0. Sci Rep. 2019. PMID: 30755669 Free PMC article.

7

Nanobodies Targeting Prostate-Specific Membrane Antigen for the Imaging and Therapy of Prostate Cancer.

Rosenfeld L, Sananes A, Zur Y, Cohen S, Dhara K, Gelkop S, Ben Zeev E, Shahar A, Lobel L, Akabayov B, Arbely E, Papo N. Rosenfeld L, et al. Among authors: papo n. J Med Chem. 2020 Jul 23;63(14):7601-7615. doi: 10.1021/acs.jmedchem.0c00418. Epub 2020 Jun 8. J Med Chem. 2020. PMID: 32442375 Free PMC article.

8

A KLK4 proteinase substrate capture approach to antagonize PAR1.

Rabinovitch E, Mihara K, Sananes A, Zaretsky M, Heyne M, Shifman J, Aharoni A, Hollenberg MD, Papo N. Rabinovitch E, et al. Among authors: papo n. Sci Rep. 2021 Aug 9;11(1):16170. doi: 10.1038/s41598-021-95666-4. Sci Rep. 2021. PMID: 34373558 Free PMC article.

9

Candido JB, Maiques O, Boxberg M, Kast V, Peerani E, Tomás-Bort E, Weichert W, Sananes A, Papo N, Magdolen V, Sanz-Moreno V, Loessner D. Candido JB, et al. Among authors: papo n. Cancers (Basel). 2021 Aug 5;13(16):3969. doi: 10.3390/cancers13163969. Cancers (Basel). 2021. PMID: 34439122 Free PMC article.

10

Bioorthogonal PEGylation Prolongs the Elimination Half-Life of N-TIMP2 While Retaining MMP Inhibition.

Hayun H, Arkadash V, Sananes A, Arbely E, Stepensky D, Papo N. Hayun H, et al. Among authors: papo n. Bioconjug Chem. 2022 May 18;33(5):795-806. doi: 10.1021/acs.bioconjchem.2c00059. Epub 2022 Apr 21. Bioconjug Chem. 2022. PMID: 35446024

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