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5-Aza-2'-deoxycytidin (Decitabine) increases cancer-testis antigen expression in head and neck squamous cell carcinoma and modifies immune checkpoint expression, especially in CD39-positive CD8 and CD4 T cells.
Fehn A, von Witzleben A, Grages A, Kors TA, Ezić J, Betzler AC, Brunner C, Schuler PJ, Theodoraki MN, Hoffmann TK, Laban S. Fehn A, et al. Among authors: schuler pj. Neoplasia. 2024 Nov 27;59:101086. doi: 10.1016/j.neo.2024.101086. Online ahead of print. Neoplasia. 2024. PMID: 39608124
Immune checkpoint expression on tumor-infiltrating lymphocytes (TIL) is dependent on HPV status in oropharyngeal carcinoma (OPSCC) - A single-cell RNA sequencing analysis.
von Witzleben A, Grages A, Thomas J, Ezić J, Brunner C, Schuler PJ, Kraus JM, Kestler HA, Vahl JM, Doescher J, King EV, Ottensmeier CH, Hoffmann TK, Laban S. von Witzleben A, et al. Among authors: schuler pj. Oral Oncol. 2024 Dec;159:107107. doi: 10.1016/j.oraloncology.2024.107107. Epub 2024 Nov 15. Oral Oncol. 2024. PMID: 39549431 Free article.
359 results