Lindorff-Larsen K - Search Results

1

Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments.

Bouchard JJ, Otero JH, Scott DC, Szulc E, Martin EW, Sabri N, Granata D, Marzahn MR, Lindorff-Larsen K, Salvatella X, Schulman BA, Mittag T. Bouchard JJ, et al. Mol Cell. 2018 Oct 4;72(1):19-36.e8. doi: 10.1016/j.molcel.2018.08.027. Epub 2018 Sep 20. Mol Cell. 2018. PMID: 30244836 Free PMC article.

2

Plant YTHDF proteins are direct effectors of antiviral immunity against an N6-methyladenosine-containing RNA virus.

Martínez-Pérez M, Aparicio F, Arribas-Hernández L, Tankmar MD, Rennie S, von Bülow S, Lindorff-Larsen K, Brodersen P, Pallas V. Martínez-Pérez M, et al. EMBO J. 2023 Sep 18;42(18):e113378. doi: 10.15252/embj.2022113378. Epub 2023 Jul 11. EMBO J. 2023. PMID: 37431920 Free PMC article.

3

Correction to "Improving Martini 3 for Disordered and Multidomain Proteins".

Thomasen FE, Pesce F, Roesgaard MA, Tesei G, Lindorff-Larsen K. Thomasen FE, et al. J Chem Theory Comput. 2023 May 23;19(10):3022-3023. doi: 10.1021/acs.jctc.3c00425. Epub 2023 May 4. J Chem Theory Comput. 2023. PMID: 37140555 No abstract available.

4

Dynamic activation and regulation of the mitogen-activated protein kinase p38.

Kumar GS, Clarkson MW, Kunze MBA, Granata D, Wand AJ, Lindorff-Larsen K, Page R, Peti W. Kumar GS, et al. Proc Natl Acad Sci U S A. 2018 May 1;115(18):4655-4660. doi: 10.1073/pnas.1721441115. Epub 2018 Apr 16. Proc Natl Acad Sci U S A. 2018. PMID: 29666261 Free PMC article.

5

Side chain to main chain hydrogen bonds stabilize a polyglutamine helix in a transcription factor.

Escobedo A, Topal B, Kunze MBA, Aranda J, Chiesa G, Mungianu D, Bernardo-Seisdedos G, Eftekharzadeh B, Gairí M, Pierattelli R, Felli IC, Diercks T, Millet O, García J, Orozco M, Crehuet R, Lindorff-Larsen K, Salvatella X. Escobedo A, et al. Nat Commun. 2019 May 2;10(1):2034. doi: 10.1038/s41467-019-09923-2. Nat Commun. 2019. PMID: 31048691 Free PMC article.

6

Interplay of folded domains and the disordered low-complexity domain in mediating hnRNPA1 phase separation.

Martin EW, Thomasen FE, Milkovic NM, Cuneo MJ, Grace CR, Nourse A, Lindorff-Larsen K, Mittag T. Martin EW, et al. Nucleic Acids Res. 2021 Mar 18;49(5):2931-2945. doi: 10.1093/nar/gkab063. Nucleic Acids Res. 2021. PMID: 33577679 Free PMC article.

7

Synergistic stabilization of a double mutant in chymotrypsin inhibitor 2 from a library screen in E. coli.

Hamborg L, Granata D, Olsen JG, Roche JV, Pedersen LE, Nielsen AT, Lindorff-Larsen K, Teilum K. Hamborg L, et al. Commun Biol. 2021 Aug 18;4(1):980. doi: 10.1038/s42003-021-02490-7. Commun Biol. 2021. PMID: 34408246 Free PMC article.

8

Conserved conformational dynamics determine enzyme activity.

Torgeson KR, Clarkson MW, Granata D, Lindorff-Larsen K, Page R, Peti W. Torgeson KR, et al. Sci Adv. 2022 Aug 5;8(31):eabo5546. doi: 10.1126/sciadv.abo5546. Epub 2022 Aug 3. Sci Adv. 2022. PMID: 35921420 Free PMC article.

9

Conformational and oligomeric states of SPOP from small-angle X-ray scattering and molecular dynamics simulations.

Thomasen FE, Cuneo MJ, Mittag T, Lindorff-Larsen K. Thomasen FE, et al. Elife. 2023 Mar 1;12:e84147. doi: 10.7554/eLife.84147. Elife. 2023. PMID: 36856266 Free PMC article.

10

Design of intrinsically disordered protein variants with diverse structural properties.

Pesce F, Bremer A, Tesei G, Hopkins JB, Grace CR, Mittag T, Lindorff-Larsen K. Pesce F, et al. bioRxiv [Preprint]. 2023 Oct 24:2023.10.22.563461. doi: 10.1101/2023.10.22.563461. bioRxiv. 2023. Update in: Sci Adv. 2024 Aug 30;10(35):eadm9926. doi: 10.1126/sciadv.adm9926 PMID: 37961110 Free PMC article. Updated. Preprint.

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