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EpCAM ectodomain EpEX is a ligand of EGFR that counteracts EGF-mediated epithelial-mesenchymal transition through modulation of phospho-ERK1/2 in head and neck cancers.
Pan M, Schinke H, Luxenburger E, Kranz G, Shakhtour J, Libl D, Huang Y, Gaber A, Pavšič M, Lenarčič B, Kitz J, Jakob M, Schwenk-Zieger S, Canis M, Hess J, Unger K, Baumeister P, Gires O. Pan M, et al. Among authors: kranz g. PLoS Biol. 2018 Sep 27;16(9):e2006624. doi: 10.1371/journal.pbio.2006624. eCollection 2018 Sep. PLoS Biol. 2018. PMID: 30261040 Free PMC article.
High Expression of EpCAM and Sox2 is a Positive Prognosticator of Clinical Outcome for Head and Neck Carcinoma.
Baumeister P, Hollmann A, Kitz J, Afthonidou A, Simon F, Shakhtour J, Mack B, Kranz G, Libl D, Leu M, Schirmer MA, Canis M, Belka C, Zitzelsberger H, Ganswindt U, Hess J, Jakob M, Unger K, Gires O. Baumeister P, et al. Among authors: kranz g. Sci Rep. 2018 Oct 1;8(1):14582. doi: 10.1038/s41598-018-32178-8. Sci Rep. 2018. PMID: 30275505 Free PMC article.
Epithelial-type systemic breast carcinoma cells with a restricted mesenchymal transition are a major source of metastasis.
Liu X, Li J, Cadilha BL, Markota A, Voigt C, Huang Z, Lin PP, Wang DD, Dai J, Kranz G, Krandick A, Libl D, Zitzelsberger H, Zagorski I, Braselmann H, Pan M, Zhu S, Huang Y, Niedermeyer S, Reichel CA, Uhl B, Briukhovetska D, Suárez J, Kobold S, Gires O, Wang H. Liu X, et al. Among authors: kranz g. Sci Adv. 2019 Jun 19;5(6):eaav4275. doi: 10.1126/sciadv.aav4275. eCollection 2019 Jun. Sci Adv. 2019. PMID: 31223646 Free PMC article.
Digital scoring of EpCAM and slug expression as prognostic markers in head and neck squamous cell carcinomas.
Schinke H, Heider T, Herkommer T, Simon F, Blancke Soares A, Kranz G, Samaga D, Dajka L, Feuchtinger A, Walch A, Valeanu L, Walz C, Kirchner T, Canis M, Baumeister P, Belka C, Maihöfer C, Marschner S, Pflugradt U, Ganswindt U, Hess J, Zitzelsberger H, Gires O. Schinke H, et al. Among authors: kranz g. Mol Oncol. 2021 Apr;15(4):1040-1053. doi: 10.1002/1878-0261.12886. Epub 2020 Dec 29. Mol Oncol. 2021. PMID: 33340247 Free PMC article.
A transcriptomic map of EGFR-induced epithelial-to-mesenchymal transition identifies prognostic and therapeutic targets for head and neck cancer.
Schinke H, Shi E, Lin Z, Quadt T, Kranz G, Zhou J, Wang H, Hess J, Heuer S, Belka C, Zitzelsberger H, Schumacher U, Genduso S, Riecken K, Gao Y, Wu Z, Reichel CA, Walz C, Canis M, Unger K, Baumeister P, Pan M, Gires O. Schinke H, et al. Among authors: kranz g. Mol Cancer. 2022 Sep 8;21(1):178. doi: 10.1186/s12943-022-01646-1. Mol Cancer. 2022. PMID: 36076232 Free PMC article.
167 results