Gait MJ - Search Results

1

Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment.

Betts CA, McClorey G, Healicon R, Hammond SM, Manzano R, Muses S, Ball V, Godfrey C, Merritt TM, van Westering T, O'Donovan L, Wells KE, Gait MJ, Wells DJ, Tyler D, Wood MJ. Betts CA, et al. Among authors: gait mj. Hum Mol Genet. 2019 Feb 1;28(3):396-406. doi: 10.1093/hmg/ddy346. Hum Mol Genet. 2019. PMID: 30281092 Free PMC article.

2

Peptide-conjugated phosphodiamidate oligomer-mediated exon skipping has benefits for cardiac function in mdx and Cmah-/-mdx mouse models of Duchenne muscular dystrophy.

Blain AM, Greally E, McClorey G, Manzano R, Betts CA, Godfrey C, O'Donovan L, Coursindel T, Gait MJ, Wood MJ, MacGowan GA, Straub VW. Blain AM, et al. Among authors: gait mj. PLoS One. 2018 Jun 18;13(6):e0198897. doi: 10.1371/journal.pone.0198897. eCollection 2018. PLoS One. 2018. PMID: 29912990 Free PMC article.

3

Diaphragm rescue alone prevents heart dysfunction in dystrophic mice.

Crisp A, Yin H, Goyenvalle A, Betts C, Moulton HM, Seow Y, Babbs A, Merritt T, Saleh AF, Gait MJ, Stuckey DJ, Clarke K, Davies KE, Wood MJ. Crisp A, et al. Among authors: gait mj. Hum Mol Genet. 2011 Feb 1;20(3):413-21. doi: 10.1093/hmg/ddq477. Epub 2010 Nov 9. Hum Mol Genet. 2011. PMID: 21062902

4

Pip5 transduction peptides direct high efficiency oligonucleotide-mediated dystrophin exon skipping in heart and phenotypic correction in mdx mice.

Yin H, Saleh AF, Betts C, Camelliti P, Seow Y, Ashraf S, Arzumanov A, Hammond S, Merritt T, Gait MJ, Wood MJ. Yin H, et al. Among authors: gait mj. Mol Ther. 2011 Jul;19(7):1295-303. doi: 10.1038/mt.2011.79. Epub 2011 Apr 19. Mol Ther. 2011. PMID: 21505427 Free PMC article.

5

Pip6-PMO, A New Generation of Peptide-oligonucleotide Conjugates With Improved Cardiac Exon Skipping Activity for DMD Treatment.

Betts C, Saleh AF, Arzumanov AA, Hammond SM, Godfrey C, Coursindel T, Gait MJ, Wood MJ. Betts C, et al. Among authors: gait mj. Mol Ther Nucleic Acids. 2012 Aug 14;1(8):e38. doi: 10.1038/mtna.2012.30. Mol Ther Nucleic Acids. 2012. PMID: 23344180 Free PMC article.

6

Prevention of exercised induced cardiomyopathy following Pip-PMO treatment in dystrophic mdx mice.

Betts CA, Saleh AF, Carr CA, Hammond SM, Coenen-Stass AM, Godfrey C, McClorey G, Varela MA, Roberts TC, Clarke K, Gait MJ, Wood MJ. Betts CA, et al. Among authors: gait mj. Sci Rep. 2015 Mar 11;5:8986. doi: 10.1038/srep08986. Sci Rep. 2015. PMID: 25758104 Free PMC article.

7

How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse.

Godfrey C, Muses S, McClorey G, Wells KE, Coursindel T, Terry RL, Betts C, Hammond S, O'Donovan L, Hildyard J, El Andaloussi S, Gait MJ, Wood MJ, Wells DJ. Godfrey C, et al. Among authors: gait mj. Hum Mol Genet. 2015 Aug 1;24(15):4225-37. doi: 10.1093/hmg/ddv155. Epub 2015 May 1. Hum Mol Genet. 2015. PMID: 25935000 Free PMC article.

8

Implications for Cardiac Function Following Rescue of the Dystrophic Diaphragm in a Mouse Model of Duchenne Muscular Dystrophy.

Betts CA, Saleh AF, Carr CA, Muses S, Wells KE, Hammond SM, Godfrey C, McClorey G, Woffindale C, Clarke K, Wells DJ, Gait MJ, Wood MJ. Betts CA, et al. Among authors: gait mj. Sci Rep. 2015 Jun 26;5:11632. doi: 10.1038/srep11632. Sci Rep. 2015. PMID: 26113184 Free PMC article.

9

Multi-level omics analysis in a murine model of dystrophin loss and therapeutic restoration.

Roberts TC, Johansson HJ, McClorey G, Godfrey C, Blomberg KE, Coursindel T, Gait MJ, Smith CI, Lehtiö J, El Andaloussi S, Wood MJ. Roberts TC, et al. Among authors: gait mj. Hum Mol Genet. 2015 Dec 1;24(23):6756-68. doi: 10.1093/hmg/ddv381. Epub 2015 Sep 18. Hum Mol Genet. 2015. PMID: 26385637 Free PMC article.

10

Bi-specific splice-switching PMO oligonucleotides conjugated via a single peptide active in a mouse model of Duchenne muscular dystrophy.

Shabanpoor F, McClorey G, Saleh AF, Järver P, Wood MJ, Gait MJ. Shabanpoor F, et al. Among authors: gait mj. Nucleic Acids Res. 2015 Jan;43(1):29-39. doi: 10.1093/nar/gku1256. Epub 2014 Dec 2. Nucleic Acids Res. 2015. PMID: 25468897 Free PMC article.

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