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Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment.
Betts CA, McClorey G, Healicon R, Hammond SM, Manzano R, Muses S, Ball V, Godfrey C, Merritt TM, van Westering T, O'Donovan L, Wells KE, Gait MJ, Wells DJ, Tyler D, Wood MJ. Betts CA, et al. Among authors: hammond sm. Hum Mol Genet. 2019 Feb 1;28(3):396-406. doi: 10.1093/hmg/ddy346. Hum Mol Genet. 2019. PMID: 30281092 Free PMC article.
PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation.
Ezzat K, Andaloussi SE, Zaghloul EM, Lehto T, Lindberg S, Moreno PM, Viola JR, Magdy T, Abdo R, Guterstam P, Sillard R, Hammond SM, Wood MJ, Arzumanov AA, Gait MJ, Smith CI, Hällbrink M, Langel Ü. Ezzat K, et al. Among authors: hammond sm. Nucleic Acids Res. 2011 Jul;39(12):5284-98. doi: 10.1093/nar/gkr072. Epub 2011 Feb 23. Nucleic Acids Res. 2011. PMID: 21345932 Free PMC article.
Genetic therapies for RNA mis-splicing diseases.
Hammond SM, Wood MJ. Hammond SM, et al. Trends Genet. 2011 May;27(5):196-205. doi: 10.1016/j.tig.2011.02.004. Epub 2011 Apr 15. Trends Genet. 2011. PMID: 21497936 Review.
Design and application of bispecific splice-switching oligonucleotides.
Bestas B, McClorey G, Tedebark U, Moreno PM, Roberts TC, Hammond SM, Smith CI, Wood MJ, Andaloussi SE. Bestas B, et al. Among authors: hammond sm. Nucleic Acid Ther. 2014 Feb;24(1):13-24. doi: 10.1089/nat.2013.0462. Nucleic Acid Ther. 2014. PMID: 24506779
117 results