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Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment.
Betts CA, McClorey G, Healicon R, Hammond SM, Manzano R, Muses S, Ball V, Godfrey C, Merritt TM, van Westering T, O'Donovan L, Wells KE, Gait MJ, Wells DJ, Tyler D, Wood MJ. Betts CA, et al. Among authors: wells ke. Hum Mol Genet. 2019 Feb 1;28(3):396-406. doi: 10.1093/hmg/ddy346. Hum Mol Genet. 2019. PMID: 30281092 Free PMC article.
How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse.
Godfrey C, Muses S, McClorey G, Wells KE, Coursindel T, Terry RL, Betts C, Hammond S, O'Donovan L, Hildyard J, El Andaloussi S, Gait MJ, Wood MJ, Wells DJ. Godfrey C, et al. Among authors: wells dj, wells ke. Hum Mol Genet. 2015 Aug 1;24(15):4225-37. doi: 10.1093/hmg/ddv155. Epub 2015 May 1. Hum Mol Genet. 2015. PMID: 25935000 Free PMC article.
Gene delivery to dystrophic muscle.
Wells KE, McMahon J, Foster H, Ferrer A, Wells DJ. Wells KE, et al. Among authors: wells dj. Methods Mol Biol. 2008;423:421-31. doi: 10.1007/978-1-59745-194-9_33. Methods Mol Biol. 2008. PMID: 18370219
98 results