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Effect of substituents at the C3´, C3´N, C10 and C2-meta-benzoate positions of taxane derivatives on their activity against resistant cancer cells.
Daniel P, Balušíková K, Truksa J, Černý J, Jaček M, Jelínek M, Mulenga MJV, Voráčová K, Chen L, Wei L, Sun Y, Ojima I, Kovář J. Daniel P, et al. Among authors: ojima i. Toxicol Appl Pharmacol. 2024 Aug;489:116993. doi: 10.1016/j.taap.2024.116993. Epub 2024 Jun 12. Toxicol Appl Pharmacol. 2024. PMID: 38870637
Recent advances in catalytic asymmetric synthesis.
Garg A, Rendina D, Bendale H, Akiyama T, Ojima I. Garg A, et al. Among authors: ojima i. Front Chem. 2024 May 9;12:1398397. doi: 10.3389/fchem.2024.1398397. eCollection 2024. Front Chem. 2024. PMID: 38783896 Free PMC article. Review.
Fatty acid binding protein 5 suppression attenuates obesity-induced hepatocellular carcinoma by promoting ferroptosis and intratumoral immune rewiring.
Sun J, Esplugues E, Bort A, Cardelo MP, Ruz-Maldonado I, Fernández-Tussy P, Wong C, Wang H, Ojima I, Kaczocha M, Perry R, Suárez Y, Fernández-Hernando C. Sun J, et al. Among authors: ojima i. Nat Metab. 2024 Apr;6(4):741-763. doi: 10.1038/s42255-024-01019-6. Epub 2024 Apr 25. Nat Metab. 2024. PMID: 38664583
Combination therapy of itraconazole and an acylhydrazone derivative (D13) for the treatment of sporotrichosis in cats.
Dib Ferreira Gremião I, Pereira-Oliveira GR, Pereira SA, Corrêa ML, Borba-Santos LP, Viçosa AL, Garg A, Haranahalli K, Dasilva D, Pereira de Sa N, Matos GS, Silva V, Lazzarini C, Fernandes CM, Miranda K, Artunduaga Bonilla JJ, Nunes AL, Nimrichter L, Ojima I, Mallamo J, McCarthy JB, Del Poeta M. Dib Ferreira Gremião I, et al. Among authors: ojima i. Microbiol Spectr. 2024 Jun 4;12(6):e0396723. doi: 10.1128/spectrum.03967-23. Epub 2024 Apr 22. Microbiol Spectr. 2024. PMID: 38647345 Free PMC article.
Third-generation taxanes SB-T-121605 and SB-T-121606 are effective in pancreatic ductal adenocarcinoma.
Sychra T, Spalenkova A, Balatka S, Vaclavikova R, Seborova K, Ehrlichova M, Truksa J, Sandoval-Acuña C, Nemcova V, Szabo A, Koci K, Tesarova T, Chen L, Ojima I, Oliverius M, Soucek P. Sychra T, et al. Among authors: ojima i. iScience. 2024 Jan 26;27(2):109044. doi: 10.1016/j.isci.2024.109044. eCollection 2024 Feb 16. iScience. 2024. PMID: 38357661 Free PMC article.
FABP5 Inhibition against PTEN-Mutant Therapy Resistant Prostate Cancer.
Swamynathan MM, Mathew G, Aziz A, Gordon C, Hillowe A, Wang H, Jhaveri A, Kendall J, Cox H, Giarrizzo M, Azabdaftari G, Rizzo RC, Diermeier SD, Ojima I, Bialkowska AB, Kaczocha M, Trotman LC. Swamynathan MM, et al. Among authors: ojima i. Cancers (Basel). 2023 Dec 21;16(1):60. doi: 10.3390/cancers16010060. Cancers (Basel). 2023. PMID: 38201488 Free PMC article.
Fatty acid binding protein 5 inhibition attenuates pronociceptive cytokine/chemokine expression and suppresses osteoarthritis pain: A comparative human and rat study.
Gordon C, Trainor J, Shah RJ, Studholme K, Gelman A, Doswell F, Sadar F, Giovannetti A, Gershenson J, Khan A, Nicholson J, Huang Z, Spurgat M, Tang SJ, Wang H, Ojima I, Carlson D, Komatsu DE, Kaczocha M. Gordon C, et al. Among authors: ojima i. Osteoarthritis Cartilage. 2024 Mar;32(3):266-280. doi: 10.1016/j.joca.2023.11.010. Epub 2023 Nov 28. Osteoarthritis Cartilage. 2024. PMID: 38035977
226 results