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Epidermal growth factor receptor (EGFR) is overexpressed in anaplastic thyroid cancer, and the EGFR inhibitor gefitinib inhibits the growth of anaplastic thyroid cancer.
Schiff BA, McMurphy AB, Jasser SA, Younes MN, Doan D, Yigitbasi OG, Kim S, Zhou G, Mandal M, Bekele BN, Holsinger FC, Sherman SI, Yeung SC, El-Naggar AK, Myers JN. Schiff BA, et al. Among authors: kim s. Clin Cancer Res. 2004 Dec 15;10(24):8594-602. doi: 10.1158/1078-0432.CCR-04-0690. Clin Cancer Res. 2004. PMID: 15623643
Induction docetaxel, cisplatin, and cetuximab followed by concurrent radiotherapy, cisplatin, and cetuximab and maintenance cetuximab in patients with locally advanced head and neck cancer.
Argiris A, Heron DE, Smith RP, Kim S, Gibson MK, Lai SY, Branstetter BF, Posluszny DM, Wang L, Seethala RR, Dacic S, Gooding W, Grandis JR, Johnson JT, Ferris RL. Argiris A, et al. Among authors: kim s. J Clin Oncol. 2010 Dec 20;28(36):5294-300. doi: 10.1200/JCO.2010.30.6423. Epub 2010 Nov 15. J Clin Oncol. 2010. PMID: 21079141 Free PMC article.
Early tumor progression associated with enhanced EGFR signaling with bortezomib, cetuximab, and radiotherapy for head and neck cancer.
Argiris A, Duffy AG, Kummar S, Simone NL, Arai Y, Kim SW, Rudy SF, Kannabiran VR, Yang X, Jang M, Chen Z, Suksta N, Cooley-Zgela T, Ramanand SG, Ahsan A, Nyati MK, Wright JJ, Van Waes C. Argiris A, et al. Among authors: kim sw. Clin Cancer Res. 2011 Sep 1;17(17):5755-64. doi: 10.1158/1078-0432.CCR-11-0861. Epub 2011 Jul 12. Clin Cancer Res. 2011. PMID: 21750205 Free PMC article. Clinical Trial.
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