Fay A - Search Results

1

Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism.

Peek J, Lilic M, Montiel D, Milshteyn A, Woodworth I, Biggins JB, Ternei MA, Calle PY, Danziger M, Warrier T, Saito K, Braffman N, Fay A, Glickman MS, Darst SA, Campbell EA, Brady SF. Peek J, et al. Among authors: fay a. Nat Commun. 2018 Oct 8;9(1):4147. doi: 10.1038/s41467-018-06587-2. Nat Commun. 2018. PMID: 30297823 Free PMC article.

2

An essential nonredundant role for mycobacterial DnaK in native protein folding.

Fay A, Glickman MS. Fay A, et al. PLoS Genet. 2014 Jul 24;10(7):e1004516. doi: 10.1371/journal.pgen.1004516. eCollection 2014 Jul. PLoS Genet. 2014. PMID: 25058675 Free PMC article.

3

Novel imidazoline antimicrobial scaffold that inhibits DNA replication with activity against mycobacteria and drug resistant Gram-positive cocci.

Harris KK, Fay A, Yan HG, Kunwar P, Socci ND, Pottabathini N, Juventhala RR, Djaballah H, Glickman MS. Harris KK, et al. Among authors: fay a. ACS Chem Biol. 2014 Nov 21;9(11):2572-83. doi: 10.1021/cb500573z. Epub 2014 Sep 15. ACS Chem Biol. 2014. PMID: 25222597 Free PMC article.

4

Reconstitution of a Mycobacterium tuberculosis proteostasis network highlights essential cofactor interactions with chaperone DnaK.

Lupoli TJ, Fay A, Adura C, Glickman MS, Nathan CF. Lupoli TJ, et al. Among authors: fay a. Proc Natl Acad Sci U S A. 2016 Dec 6;113(49):E7947-E7956. doi: 10.1073/pnas.1617644113. Epub 2016 Nov 21. Proc Natl Acad Sci U S A. 2016. PMID: 27872278 Free PMC article.

5

Structure and function of the mycobacterial transcription initiation complex with the essential regulator RbpA.

Hubin EA, Fay A, Xu C, Bean JM, Saecker RM, Glickman MS, Darst SA, Campbell EA. Hubin EA, et al. Among authors: fay a. Elife. 2017 Jan 9;6:e22520. doi: 10.7554/eLife.22520. Elife. 2017. PMID: 28067618 Free PMC article.

6

Control of biotin biosynthesis in mycobacteria by a pyruvate carboxylase dependent metabolic signal.

Lazar N, Fay A, Nandakumar M, Boyle KE, Xavier J, Rhee K, Glickman MS. Lazar N, et al. Among authors: fay a. Mol Microbiol. 2017 Dec;106(6):1018-1031. doi: 10.1111/mmi.13865. Epub 2017 Nov 17. Mol Microbiol. 2017. PMID: 29052269 Free PMC article.

7

Two Accessory Proteins Govern MmpL3 Mycolic Acid Transport in Mycobacteria.

Fay A, Czudnochowski N, Rock JM, Johnson JR, Krogan NJ, Rosenberg O, Glickman MS. Fay A, et al. mBio. 2019 Jun 25;10(3):e00850-19. doi: 10.1128/mBio.00850-19. mBio. 2019. PMID: 31239378 Free PMC article.

8

The DnaK Chaperone System Buffers the Fitness Cost of Antibiotic Resistance Mutations in Mycobacteria.

Fay A, Philip J, Saha P, Hendrickson RC, Glickman MS, Burns-Huang K. Fay A, et al. mBio. 2021 Mar 30;12(2):e00123-21. doi: 10.1128/mBio.00123-21. mBio. 2021. PMID: 33785614 Free PMC article.

9

Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system.

Yin Y, Feng X, Yu H, Fay A, Kovach A, Glickman MS, Li H. Yin Y, et al. Among authors: fay a. Cell Rep. 2021 May 25;35(8):109166. doi: 10.1016/j.celrep.2021.109166. Cell Rep. 2021. PMID: 34038719 Free PMC article.

10

Mycobacterial helicase Lhr abets resistance to DNA crosslinking agents mitomycin C and cisplatin.

Warren GM, Ejaz A, Fay A, Glickman MS, Shuman S. Warren GM, et al. Among authors: fay a. Nucleic Acids Res. 2023 Jan 11;51(1):218-235. doi: 10.1093/nar/gkac1222. Nucleic Acids Res. 2023. PMID: 36610794 Free PMC article.

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