Namasivayam V - Search Results

1

Development of a selective and highly sensitive fluorescence assay for nucleoside triphosphate diphosphohydrolase1 (NTPDase1, CD39).

Lee SY , Luo X , Namasivayam V , Geiss J , Mirza S , Pelletier J , Stephan H , Sévigny J , Müller CE . Lee SY , et al. Among authors: namasivayam v. Analyst. 2018 Nov 5;143(22):5417-5430. doi: 10.1039/c8an01108g. Analyst. 2018. PMID: 30303204

2

Role of extracellular cysteine residues in the adenosine A2A receptor.

De Filippo E, Namasivayam V, Zappe L, El-Tayeb A, Schiedel AC, Müller CE. De Filippo E, et al. Among authors: namasivayam v. Purinergic Signal. 2016 Jun;12(2):313-29. doi: 10.1007/s11302-016-9506-7. Epub 2016 Mar 11. Purinergic Signal. 2016. PMID: 26969588 Free PMC article.

3

Characterization of P2X4 receptor agonists and antagonists by calcium influx and radioligand binding studies.

Abdelrahman A, Namasivayam V, Hinz S, Schiedel AC, Köse M, Burton M, El-Tayeb A, Gillard M, Bajorath J, de Ryck M, Müller CE. Abdelrahman A, et al. Among authors: namasivayam v. Biochem Pharmacol. 2017 Feb 1;125:41-54. doi: 10.1016/j.bcp.2016.11.016. Epub 2016 Nov 17. Biochem Pharmacol. 2017. PMID: 27867013

4

The promiscuous ectonucleotidase NPP1: molecular insights into substrate binding and hydrolysis.

Namasivayam V, Lee SY, Müller CE. Namasivayam V, et al. Biochim Biophys Acta Gen Subj. 2017 Mar;1861(3):603-614. doi: 10.1016/j.bbagen.2016.12.019. Epub 2016 Dec 21. Biochim Biophys Acta Gen Subj. 2017. PMID: 28011303 No abstract available.

5

Interaction of Approved Drugs with Synaptic Vesicle Protein 2A.

Danish A, Namasivayam V, Schiedel AC, Müller CE. Danish A, et al. Among authors: namasivayam v. Arch Pharm (Weinheim). 2017 Apr;350(3-4). doi: 10.1002/ardp.201700003. Epub 2017 Feb 21. Arch Pharm (Weinheim). 2017. PMID: 28220535

6

Substrate-Dependence of Competitive Nucleotide Pyrophosphatase/Phosphodiesterase1 (NPP1) Inhibitors.

Lee SY, Sarkar S, Bhattarai S, Namasivayam V, De Jonghe S, Stephan H, Herdewijn P, El-Tayeb A, Müller CE. Lee SY, et al. Among authors: namasivayam v. Front Pharmacol. 2017 Feb 15;8:54. doi: 10.3389/fphar.2017.00054. eCollection 2017. Front Pharmacol. 2017. PMID: 28261095 Free PMC article.

7

Development of Potent and Selective Antagonists for the UTP-Activated P2Y₄ Receptor.

Rafehi M, Malik EM, Neumann A, Abdelrahman A, Hanck T, Namasivayam V, Müller CE, Baqi Y. Rafehi M, et al. Among authors: namasivayam v. J Med Chem. 2017 Apr 13;60(7):3020-3038. doi: 10.1021/acs.jmedchem.7b00030. Epub 2017 Mar 30. J Med Chem. 2017. PMID: 28306255

8

Molecular Recognition of Agonists and Antagonists by the Nucleotide-Activated G Protein-Coupled P2Y₂ Receptor.

Rafehi M, Neumann A, Baqi Y, Malik EM, Wiese M, Namasivayam V, Müller CE. Rafehi M, et al. Among authors: namasivayam v. J Med Chem. 2017 Oct 26;60(20):8425-8440. doi: 10.1021/acs.jmedchem.7b00854. Epub 2017 Oct 10. J Med Chem. 2017. PMID: 28938069

9

Fluorescent-Labeled Selective Adenosine A_2B Receptor Antagonist Enables Competition Binding Assay by Flow Cytometry.

Köse M, Gollos S, Karcz T, Fiene A, Heisig F, Behrenswerth A, Kieć-Kononowicz K, Namasivayam V, Müller CE. Köse M, et al. Among authors: namasivayam v. J Med Chem. 2018 May 24;61(10):4301-4316. doi: 10.1021/acs.jmedchem.7b01627. Epub 2018 May 15. J Med Chem. 2018. PMID: 29681156

10

Probing Substituents in the 1- and 3-Position: Tetrahydropyrazino-Annelated Water-Soluble Xanthine Derivatives as Multi-Target Drugs With Potent Adenosine Receptor Antagonistic Activity.

Koch P, Brunschweiger A, Namasivayam V, Ullrich S, Maruca A, Lazzaretto B, Küppers P, Hinz S, Hockemeyer J, Wiese M, Heer J, Alcaro S, Kiec-Kononowicz K, Müller CE. Koch P, et al. Among authors: namasivayam v. Front Chem. 2018 Jun 26;6:206. doi: 10.3389/fchem.2018.00206. eCollection 2018. Front Chem. 2018. PMID: 29998095 Free PMC article.

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