Scott I - Search Results

1

The protein acetylase GCN5L1 modulates hepatic fatty acid oxidation activity via acetylation of the mitochondrial β-oxidation enzyme HADHA.

Thapa D, Wu K, Stoner MW, Xie B, Zhang M, Manning JR, Lu Z, Li JH, Chen Y, Gucek M, Playford MP, Mehta NN, Harmon D, O'Doherty RM, Jurczak MJ, Sack MN, Scott I. Thapa D, et al. Among authors: scott i. J Biol Chem. 2018 Nov 16;293(46):17676-17684. doi: 10.1074/jbc.AC118.005462. Epub 2018 Oct 15. J Biol Chem. 2018. PMID: 30323061 Free PMC article.

2

The emerging characterization of lysine residue deacetylation on the modulation of mitochondrial function and cardiovascular biology.

Lu Z, Scott I, Webster BR, Sack MN. Lu Z, et al. Among authors: scott i. Circ Res. 2009 Oct 23;105(9):830-41. doi: 10.1161/CIRCRESAHA.109.204974. Circ Res. 2009. PMID: 19850949 Free PMC article. Review.

3

SIRT3 is regulated by nutrient excess and modulates hepatic susceptibility to lipotoxicity.

Bao J, Scott I, Lu Z, Pang L, Dimond CC, Gius D, Sack MN. Bao J, et al. Among authors: scott i. Free Radic Biol Med. 2010 Oct 15;49(7):1230-7. doi: 10.1016/j.freeradbiomed.2010.07.009. Epub 2010 Jul 18. Free Radic Biol Med. 2010. PMID: 20647045 Free PMC article.

4

The role of sirtuins in modulating redox stressors.

Webster BR, Lu Z, Sack MN, Scott I. Webster BR, et al. Among authors: scott i. Free Radic Biol Med. 2012 Jan 15;52(2):281-90. doi: 10.1016/j.freeradbiomed.2011.10.484. Epub 2011 Oct 31. Free Radic Biol Med. 2012. PMID: 22085655 Free PMC article. Review.

5

Identification of a molecular component of the mitochondrial acetyltransferase programme: a novel role for GCN5L1.

Scott I, Webster BR, Li JH, Sack MN. Scott I, et al. Biochem J. 2012 May 1;443(3):655-61. doi: 10.1042/BJ20120118. Biochem J. 2012. PMID: 22309213 Free PMC article.

6

Restricted mitochondrial protein acetylation initiates mitochondrial autophagy.

Webster BR, Scott I, Han K, Li JH, Lu Z, Stevens MV, Malide D, Chen Y, Samsel L, Connelly PS, Daniels MP, McCoy JP Jr, Combs CA, Gucek M, Sack MN. Webster BR, et al. Among authors: scott i. J Cell Sci. 2013 Nov 1;126(Pt 21):4843-9. doi: 10.1242/jcs.131300. Epub 2013 Sep 4. J Cell Sci. 2013. PMID: 24006259 Free PMC article.

7

GCN5-like protein 1 (GCN5L1) controls mitochondrial content through coordinated regulation of mitochondrial biogenesis and mitophagy.

Scott I, Webster BR, Chan CK, Okonkwo JU, Han K, Sack MN. Scott I, et al. J Biol Chem. 2014 Jan 31;289(5):2864-72. doi: 10.1074/jbc.M113.521641. Epub 2013 Dec 19. J Biol Chem. 2014. PMID: 24356961 Free PMC article.

8

Regulation of autophagy and mitophagy by nutrient availability and acetylation.

Webster BR, Scott I, Traba J, Han K, Sack MN. Webster BR, et al. Among authors: scott i. Biochim Biophys Acta. 2014 Apr 4;1841(4):525-34. doi: 10.1016/j.bbalip.2014.02.001. Epub 2014 Feb 11. Biochim Biophys Acta. 2014. PMID: 24525425 Free PMC article. Review.

9

α-Lipoic acid promotes α-tubulin hyperacetylation and blocks the turnover of mitochondria through mitophagy.

Stoner MW, Thapa D, Zhang M, Gibson GA, Calderon MJ, St Croix CM, Scott I. Stoner MW, et al. Among authors: scott i. Biochem J. 2016 Jun 15;473(12):1821-30. doi: 10.1042/BCJ20160281. Epub 2016 Apr 20. Biochem J. 2016. PMID: 27099338 Free PMC article.

10

Acetylation of mitochondrial proteins by GCN5L1 promotes enhanced fatty acid oxidation in the heart.

Thapa D, Zhang M, Manning JR, Guimarães DA, Stoner MW, O'Doherty RM, Shiva S, Scott I. Thapa D, et al. Among authors: scott i. Am J Physiol Heart Circ Physiol. 2017 Aug 1;313(2):H265-H274. doi: 10.1152/ajpheart.00752.2016. Epub 2017 May 19. Am J Physiol Heart Circ Physiol. 2017. PMID: 28526709 Free PMC article.

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