Chen H - Search Results

1

Complementary Wnt Sources Regulate Lymphatic Vascular Development via PROX1-Dependent Wnt/β-Catenin Signaling.

Cha B, Geng X, Mahamud MR, Zhang JY, Chen L, Kim W, Jho EH, Kim Y, Choi D, Dixon JB, Chen H, Hong YK, Olson L, Kim TH, Merrill BJ, Davis MJ, Srinivasan RS. Cha B, et al. Among authors: chen l, chen h. Cell Rep. 2018 Oct 16;25(3):571-584.e5. doi: 10.1016/j.celrep.2018.09.049. Cell Rep. 2018. PMID: 30332639 Free PMC article.

2

Molecular and cellular mechanisms of lymphatic vascular maturation.

Chen H, Griffin C, Xia L, Srinivasan RS. Chen H, et al. Microvasc Res. 2014 Nov;96:16-22. doi: 10.1016/j.mvr.2014.06.002. Epub 2014 Jun 11. Microvasc Res. 2014. PMID: 24928499 Free PMC article. Review.

3

Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function.

Liu X, Pasula S, Song H, Tessneer KL, Dong Y, Hahn S, Yago T, Brophy ML, Chang B, Cai X, Wu H, McManus J, Ichise H, Georgescu C, Wren JD, Griffin C, Xia L, Srinivasan RS, Chen H. Liu X, et al. Among authors: chen h. Sci Signal. 2014 Oct 14;7(347):ra97. doi: 10.1126/scisignal.2005413. Sci Signal. 2014. PMID: 25314967 Free PMC article.

4

Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development.

Geng X, Cha B, Mahamud MR, Lim KC, Silasi-Mansat R, Uddin MKM, Miura N, Xia L, Simon AM, Engel JD, Chen H, Lupu F, Srinivasan RS. Geng X, et al. Among authors: chen h. Dev Biol. 2016 Jan 1;409(1):218-233. doi: 10.1016/j.ydbio.2015.10.022. Epub 2015 Nov 2. Dev Biol. 2016. PMID: 26542011 Free PMC article.

5

Selective Targeting of a Novel Epsin-VEGFR2 Interaction Promotes VEGF-Mediated Angiogenesis.

Rahman HNA, Wu H, Dong Y, Pasula S, Wen A, Sun Y, Brophy ML, Tessneer KL, Cai X, McManus J, Chang B, Kwak S, Rahman NS, Xu W, Fernandes C, Mcdaniel JM, Xia L, Smith L, Srinivasan RS, Chen H. Rahman HNA, et al. Among authors: chen h. Circ Res. 2016 Mar 18;118(6):957-969. doi: 10.1161/CIRCRESAHA.115.307679. Epub 2016 Feb 15. Circ Res. 2016. PMID: 26879230 Free PMC article.

6

Mechanotransduction activates canonical Wnt/β-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves.

Cha B, Geng X, Mahamud MR, Fu J, Mukherjee A, Kim Y, Jho EH, Kim TH, Kahn ML, Xia L, Dixon JB, Chen H, Srinivasan RS. Cha B, et al. Among authors: chen h. Genes Dev. 2016 Jun 15;30(12):1454-69. doi: 10.1101/gad.282400.116. Epub 2016 Jun 16. Genes Dev. 2016. PMID: 27313318 Free PMC article.

7

Epsin deficiency promotes lymphangiogenesis through regulation of VEGFR3 degradation in diabetes.

Wu H, Rahman HNA, Dong Y, Liu X, Lee Y, Wen A, To KH, Xiao L, Birsner AE, Bazinet L, Wong S, Song K, Brophy ML, Mahamud MR, Chang B, Cai X, Pasula S, Kwak S, Yang W, Bischoff J, Xu J, Bielenberg DR, Dixon JB, D'Amato RJ, Srinivasan RS, Chen H. Wu H, et al. Among authors: chen h. J Clin Invest. 2018 Aug 31;128(9):4025-4043. doi: 10.1172/JCI96063. Epub 2018 Aug 13. J Clin Invest. 2018. PMID: 30102256 Free PMC article.

8

GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126.

Mahamud MR, Geng X, Ho YC, Cha B, Kim Y, Ma J, Chen L, Myers G, Camper S, Mustacich D, Witte M, Choi D, Hong YK, Chen H, Varshney G, Engel JD, Wang S, Kim TH, Lim KC, Srinivasan RS. Mahamud MR, et al. Among authors: chen l, chen h. Development. 2019 Nov 5;146(21):dev184218. doi: 10.1242/dev.184218. Development. 2019. PMID: 31582413 Free PMC article.

9

S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling.

Geng X, Yanagida K, Akwii RG, Choi D, Chen L, Ho Y, Cha B, Mahamud MR, Berman de Ruiz K, Ichise H, Chen H, Wythe JD, Mikelis CM, Hla T, Srinivasan RS. Geng X, et al. Among authors: chen l, chen h. JCI Insight. 2020 Jul 23;5(14):e137652. doi: 10.1172/jci.insight.137652. JCI Insight. 2020. PMID: 32544090 Free PMC article.

10

YAP and TAZ maintain PROX1 expression in the developing lymphatic and lymphovenous valves in response to VEGF-C signaling.

Cha B, Ho YC, Geng X, Mahamud MR, Chen L, Kim Y, Choi D, Kim TH, Randolph GJ, Cao X, Chen H, Srinivasan RS. Cha B, et al. Among authors: chen l, chen h. Development. 2020 Dec 13;147(23):dev195453. doi: 10.1242/dev.195453. Development. 2020. PMID: 33060128 Free PMC article.

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