Hart PJ - Search Results

1

Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents.

Rugel A, Tarpley RS, Lopez A, Menard T, Guzman MA, Taylor AB, Cao X, Kovalskyy D, Chevalier FD, Anderson TJC, Hart PJ, LoVerde PT, McHardy SF. Rugel A, et al. Among authors: hart pj. ACS Med Chem Lett. 2018 Sep 14;9(10):967-973. doi: 10.1021/acsmedchemlett.8b00257. eCollection 2018 Oct 11. ACS Med Chem Lett. 2018. PMID: 30344901 Free PMC article.

2

Crystal structure of the human TbetaR2 ectodomain--TGF-beta3 complex.

Hart PJ, Deep S, Taylor AB, Shu Z, Hinck CS, Hinck AP. Hart PJ, et al. Nat Struct Biol. 2002 Mar;9(3):203-8. doi: 10.1038/nsb766. Nat Struct Biol. 2002. PMID: 11850637

3

Copper chaperones.

Elam JS, Thomas ST, Holloway SP, Taylor AB, Hart PJ. Elam JS, et al. Among authors: hart pj. Adv Protein Chem. 2002;60:151-219. doi: 10.1016/s0065-3233(02)60054-3. Adv Protein Chem. 2002. PMID: 12418178 Review. No abstract available.

4

An alternative mechanism of bicarbonate-mediated peroxidation by copper-zinc superoxide dismutase: rates enhanced via proposed enzyme-associated peroxycarbonate intermediate.

Elam JS, Malek K, Rodriguez JA, Doucette PA, Taylor AB, Hayward LJ, Cabelli DE, Valentine JS, Hart PJ. Elam JS, et al. Among authors: hart pj. J Biol Chem. 2003 Jun 6;278(23):21032-9. doi: 10.1074/jbc.M300484200. Epub 2003 Mar 20. J Biol Chem. 2003. PMID: 12649272 Free article.

5

Structure-function analysis of the auxilin J-domain reveals an extended Hsc70 interaction interface.

Jiang J, Taylor AB, Prasad K, Ishikawa-Brush Y, Hart PJ, Lafer EM, Sousa R. Jiang J, et al. Among authors: hart pj. Biochemistry. 2003 May 20;42(19):5748-53. doi: 10.1021/bi034270g. Biochemistry. 2003. PMID: 12741832

6

Amyloid-like filaments and water-filled nanotubes formed by SOD1 mutant proteins linked to familial ALS.

Elam JS, Taylor AB, Strange R, Antonyuk S, Doucette PA, Rodriguez JA, Hasnain SS, Hayward LJ, Valentine JS, Yeates TO, Hart PJ. Elam JS, et al. Among authors: hart pj. Nat Struct Biol. 2003 Jun;10(6):461-7. doi: 10.1038/nsb935. Nat Struct Biol. 2003. PMID: 12754496

7

Structure of Mycobacterium tuberculosis methionine sulfoxide reductase A in complex with protein-bound methionine.

Taylor AB, Benglis DM Jr, Dhandayuthapani S, Hart PJ. Taylor AB, et al. Among authors: hart pj. J Bacteriol. 2003 Jul;185(14):4119-26. doi: 10.1128/JB.185.14.4119-4126.2003. J Bacteriol. 2003. PMID: 12837786 Free PMC article.

8

Dissociation of human copper-zinc superoxide dismutase dimers using chaotrope and reductant. Insights into the molecular basis for dimer stability.

Doucette PA, Whitson LJ, Cao X, Schirf V, Demeler B, Valentine JS, Hansen JC, Hart PJ. Doucette PA, et al. Among authors: hart pj. J Biol Chem. 2004 Dec 24;279(52):54558-66. doi: 10.1074/jbc.M409744200. Epub 2004 Oct 12. J Biol Chem. 2004. PMID: 15485869 Free article.

9

Proteasomal degradation of mutant superoxide dismutases linked to amyotrophic lateral sclerosis.

Di Noto L, Whitson LJ, Cao X, Hart PJ, Levine RL. Di Noto L, et al. Among authors: hart pj. J Biol Chem. 2005 Dec 2;280(48):39907-13. doi: 10.1074/jbc.M506247200. Epub 2005 Sep 29. J Biol Chem. 2005. PMID: 16195234 Free article.

10

The copper-iron connection in biology: structure of the metallo-oxidase Fet3p.

Taylor AB, Stoj CS, Ziegler L, Kosman DJ, Hart PJ. Taylor AB, et al. Among authors: hart pj. Proc Natl Acad Sci U S A. 2005 Oct 25;102(43):15459-64. doi: 10.1073/pnas.0506227102. Epub 2005 Oct 17. Proc Natl Acad Sci U S A. 2005. PMID: 16230618 Free PMC article.

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