Theobald DL - Search Results

1

Functional and Structural Resilience of the Active Site Loop in the Evolution of Plasmodium Lactate Dehydrogenase.

Wirth JD, Boucher JI, Jacobowitz JR, Classen S, Theobald DL. Wirth JD, et al. Among authors: theobald dl. Biochemistry. 2018 Nov 13;57(45):6434-6442. doi: 10.1021/acs.biochem.8b00913. Epub 2018 Nov 2. Biochemistry. 2018. PMID: 30358994 Free PMC article.

2

Relocating the active-site lysine in rhodopsin and implications for evolution of retinylidene proteins.

Devine EL, Oprian DD, Theobald DL. Devine EL, et al. Among authors: theobald dl. Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13351-5. doi: 10.1073/pnas.1306826110. Epub 2013 Jul 31. Proc Natl Acad Sci U S A. 2013. PMID: 23904486 Free PMC article.

3

An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases.

Boucher JI, Jacobowitz JR, Beckett BC, Classen S, Theobald DL. Boucher JI, et al. Among authors: theobald dl. Elife. 2014 Jun 25;3:e02304. doi: 10.7554/eLife.02304. Elife. 2014. PMID: 24966208 Free PMC article.

4

Gradual neofunctionalization in the convergent evolution of trichomonad lactate and malate dehydrogenases.

Steindel PA, Chen EH, Wirth JD, Theobald DL. Steindel PA, et al. Among authors: theobald dl. Protein Sci. 2016 Jul;25(7):1319-31. doi: 10.1002/pro.2904. Epub 2016 Mar 24. Protein Sci. 2016. PMID: 26889885 Free PMC article.

5

Relocating the Active-Site Lysine in Rhodopsin: 2. Evolutionary Intermediates.

Devine EL, Theobald DL, Oprian DD. Devine EL, et al. Among authors: theobald dl. Biochemistry. 2016 Aug 30;55(34):4864-70. doi: 10.1021/acs.biochem.6b00478. Epub 2016 Aug 12. Biochemistry. 2016. PMID: 27486845 Free PMC article.

6

Purification and Characterization of RhoPDE, a Retinylidene/Phosphodiesterase Fusion Protein and Potential Optogenetic Tool from the Choanoflagellate Salpingoeca rosetta.

Lamarche LB, Kumar RP, Trieu MM, Devine EL, Cohen-Abeles LE, Theobald DL, Oprian DD. Lamarche LB, et al. Among authors: theobald dl. Biochemistry. 2017 Oct 31;56(43):5812-5822. doi: 10.1021/acs.biochem.7b00519. Epub 2017 Oct 18. Biochemistry. 2017. PMID: 28976747 Free PMC article.

7

Crystal Structure of Caryolan-1-ol Synthase, a Sesquiterpene Synthase Catalyzing an Initial Anti-Markovnikov Cyclization Reaction.

Kumar RP, Matos JO, Black BY, Ellenburg WH, Chen J, Patterson M, Gehtman JA, Theobald DL, Krauss IJ, Oprian DD. Kumar RP, et al. Among authors: theobald dl. Biochemistry. 2024 Nov 5;63(21):2904-2915. doi: 10.1021/acs.biochem.4c00547. Epub 2024 Oct 14. Biochemistry. 2024. PMID: 39400323

8

An empirical test of convergent evolution in rhodopsins.

Mackin KA, Roy RA, Theobald DL. Mackin KA, et al. Among authors: theobald dl. Mol Biol Evol. 2014 Jan;31(1):85-95. doi: 10.1093/molbev/mst171. Epub 2013 Sep 27. Mol Biol Evol. 2014. PMID: 24077848 Free PMC article.

9

Presenilin adopts the ClC channel fold.

Theobald DL. Theobald DL. Protein Sci. 2016 Jul;25(7):1363-5. doi: 10.1002/pro.2919. Epub 2016 Mar 23. Protein Sci. 2016. PMID: 26971579 Free PMC article.

10

A thermodynamic model of protein structure evolution explains empirical amino acid substitution matrices.

Norn C, André I, Theobald DL. Norn C, et al. Among authors: theobald dl. Protein Sci. 2021 Oct;30(10):2057-2068. doi: 10.1002/pro.4155. Epub 2021 Jul 30. Protein Sci. 2021. PMID: 34218472 Free PMC article.

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