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The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin.
Hayes JD, Chanas SA, Henderson CJ, McMahon M, Sun C, Moffat GJ, Wolf CR, Yamamoto M. Hayes JD, et al. Among authors: mcmahon m. Biochem Soc Trans. 2000 Feb;28(2):33-41. doi: 10.1042/bst0280033. Biochem Soc Trans. 2000. PMID: 10816095
Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice.
Chanas SA, Jiang Q, McMahon M, McWalter GK, McLellan LI, Elcombe CR, Henderson CJ, Wolf CR, Moffat GJ, Itoh K, Yamamoto M, Hayes JD. Chanas SA, et al. Among authors: mcmahon m. Biochem J. 2002 Jul 15;365(Pt 2):405-16. doi: 10.1042/BJ20020320. Biochem J. 2002. PMID: 11991805 Free PMC article.
1,508 results