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A CARD9 Founder Mutation Disrupts NF-κB Signaling by Inhibiting BCL10 and MALT1 Recruitment and Signalosome Formation.
De Bruyne M, Hoste L, Bogaert DJ, Van den Bossche L, Tavernier SJ, Parthoens E, Migaud M, Konopnicki D, Yombi JC, Lambrecht BN, van Daele S, Alves de Medeiros AK, Brochez L, Beyaert R, De Baere E, Puel A, Casanova JL, Goffard JC, Savvides SN, Haerynck F, Staal J, Dullaers M. De Bruyne M, et al. Among authors: lambrecht bn. Front Immunol. 2018 Oct 31;9:2366. doi: 10.3389/fimmu.2018.02366. eCollection 2018. Front Immunol. 2018. PMID: 30429846 Free PMC article.
The ubiquitin-editing protein A20 prevents dendritic cell activation, recognition of apoptotic cells, and systemic autoimmunity.
Kool M, van Loo G, Waelput W, De Prijck S, Muskens F, Sze M, van Praet J, Branco-Madeira F, Janssens S, Reizis B, Elewaut D, Beyaert R, Hammad H, Lambrecht BN. Kool M, et al. Among authors: lambrecht bn. Immunity. 2011 Jul 22;35(1):82-96. doi: 10.1016/j.immuni.2011.05.013. Epub 2011 Jun 30. Immunity. 2011. PMID: 21723156 Free article.
A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis.
Matmati M, Jacques P, Maelfait J, Verheugen E, Kool M, Sze M, Geboes L, Louagie E, Mc Guire C, Vereecke L, Chu Y, Boon L, Staelens S, Matthys P, Lambrecht BN, Schmidt-Supprian M, Pasparakis M, Elewaut D, Beyaert R, van Loo G. Matmati M, et al. Among authors: lambrecht bn. Nat Genet. 2011 Aug 14;43(9):908-12. doi: 10.1038/ng.874. Nat Genet. 2011. PMID: 21841782
The who, where, and when of IgE in allergic airway disease.
Dullaers M, De Bruyne R, Ramadani F, Gould HJ, Gevaert P, Lambrecht BN. Dullaers M, et al. Among authors: lambrecht bn. J Allergy Clin Immunol. 2012 Mar;129(3):635-45. doi: 10.1016/j.jaci.2011.10.029. Epub 2011 Dec 9. J Allergy Clin Immunol. 2012. PMID: 22168998 Review.
A20-deficient mast cells exacerbate inflammatory responses in vivo.
Heger K, Fierens K, Vahl JC, Aszodi A, Peschke K, Schenten D, Hammad H, Beyaert R, Saur D, van Loo G, Roers A, Lambrecht BN, Kool M, Schmidt-Supprian M. Heger K, et al. Among authors: lambrecht bn. PLoS Biol. 2014 Jan;12(1):e1001762. doi: 10.1371/journal.pbio.1001762. Epub 2014 Jan 14. PLoS Biol. 2014. PMID: 24453940 Free PMC article.
Raised immunoglobulin A and circulating T follicular helper cells are linked to the development of food allergy in paediatric liver transplant patients.
De Bruyne R, Gevaert P, Van Winckel M, De Ruyck N, Minne A, Bogaert D, Van Biervliet S, Vande Velde S, Smets F, Sokal E, Gottrand F, Vanhelst J, Detry B, Pilette C, Lambrecht BN, Dullaers M. De Bruyne R, et al. Among authors: lambrecht bn. Clin Exp Allergy. 2015 Jun;45(6):1060-70. doi: 10.1111/cea.12514. Clin Exp Allergy. 2015. PMID: 25702946
470 results