Aouad P - Search Results

1

Intraductal patient-derived xenografts of estrogen receptor α-positive breast cancer recapitulate the histopathological spectrum and metastatic potential of human lesions.

Fiche M, Scabia V, Aouad P, Battista L, Treboux A, Stravodimou A, Zaman K; RLS; Dormoy V, Ayyanan A, Sflomos G, Brisken C. Fiche M, et al. Among authors: aouad p. J Pathol. 2019 Mar;247(3):287-292. doi: 10.1002/path.5200. Epub 2018 Dec 27. J Pathol. 2019. PMID: 30430577 Free PMC article.

2

Oestrogen receptor α AF-1 and AF-2 domains have cell population-specific functions in the mammary epithelium.

Cagnet S, Ataca D, Sflomos G, Aouad P, Schuepbach-Mallepell S, Hugues H, Krust A, Ayyanan A, Scabia V, Brisken C. Cagnet S, et al. Among authors: aouad p. Nat Commun. 2018 Nov 9;9(1):4723. doi: 10.1038/s41467-018-07175-0. Nat Commun. 2018. PMID: 30413705 Free PMC article.

3

Intraductal xenografts show lobular carcinoma cells rely on their own extracellular matrix and LOXL1.

Sflomos G, Battista L, Aouad P, De Martino F, Scabia V, Stravodimou A, Ayyanan A, Ifticene-Treboux A; RLS; Bucher P, Fiche M, Ambrosini G, Brisken C. Sflomos G, et al. Among authors: aouad p. EMBO Mol Med. 2021 Mar 5;13(3):e13180. doi: 10.15252/emmm.202013180. Epub 2021 Feb 22. EMBO Mol Med. 2021. PMID: 33616307 Free PMC article.

4

Epithelial-mesenchymal plasticity determines estrogen receptor positive breast cancer dormancy and epithelial reconversion drives recurrence.

Aouad P, Zhang Y, De Martino F, Stibolt C, Ali S, Ambrosini G, Mani SA, Maggs K, Quinn HM, Sflomos G, Brisken C. Aouad P, et al. Nat Commun. 2022 Aug 25;13(1):4975. doi: 10.1038/s41467-022-32523-6. Nat Commun. 2022. PMID: 36008376 Free PMC article.

5

Tumor dormancy: EMT beyond invasion and metastasis.

Aouad P, Quinn HM, Berger A, Brisken C. Aouad P, et al. Genesis. 2024 Feb;62(1):e23552. doi: 10.1002/dvg.23552. Epub 2023 Sep 30. Genesis. 2024. PMID: 37776086 Review.

6

The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche.

Ataca D, Aouad P, Constantin C, Laszlo C, Beleut M, Shamseddin M, Rajaram RD, Jeitziner R, Mead TJ, Caikovski M, Bucher P, Ambrosini G, Apte SS, Brisken C. Ataca D, et al. Among authors: aouad p. Nat Commun. 2020 Mar 26;11(1):1571. doi: 10.1038/s41467-020-15357-y. Nat Commun. 2020. PMID: 32218432 Free PMC article.

7

An engineered multicellular stem cell niche for the 3D derivation of human myogenic progenitors from iPSCs.

Mashinchian O, De Franceschi F, Nassiri S, Michaud J, Migliavacca E, Aouad P, Metairon S, Pruvost S, Karaz S, Fabre P, Molina T, Stuelsatz P, Hegde N, Le Moal E, Dammone G, Dumont NA, Lutolf MP, Feige JN, Bentzinger CF. Mashinchian O, et al. Among authors: aouad p. EMBO J. 2022 Jul 18;41(14):e110655. doi: 10.15252/embj.2022110655. Epub 2022 Jun 15. EMBO J. 2022. PMID: 35703167 Free PMC article.

8

Antitumor activities of the synthetic retinoid ST1926 in two-dimensional and three-dimensional human breast cancer models.

Aouad P, Saikali M, Abdel-Samad R, Fostok S, El-Houjeiri L, Pisano C, Talhouk R, Darwiche N. Aouad P, et al. Anticancer Drugs. 2017 Aug;28(7):757-770. doi: 10.1097/CAD.0000000000000511. Anticancer Drugs. 2017. PMID: 28471809

9

Antitumor Effect of the Atypical Retinoid ST1926 in Acute Myeloid Leukemia and Nanoparticle Formulation Prolongs Lifespan and Reduces Tumor Burden of Xenograft Mice.

El-Houjeiri L, Saad W, Hayar B, Aouad P, Tawil N, Abdel-Samad R, Hleihel R, Hamie M, Mancinelli A, Pisano C, El Hajj H, Darwiche N. El-Houjeiri L, et al. Among authors: aouad p. Mol Cancer Ther. 2017 Oct;16(10):2047-2057. doi: 10.1158/1535-7163.MCT-16-0785. Epub 2017 Jun 15. Mol Cancer Ther. 2017. PMID: 28619754

10

Mechanism of action of the atypical retinoid ST1926 in colorectal cancer: DNA damage and DNA polymerase α.

Abdel-Samad R, Aouad P, Gali-Muhtasib H, Sweidan Z, Hmadi R, Kadara H, D'Andrea EL, Fucci A, Pisano C, Darwiche N. Abdel-Samad R, et al. Among authors: aouad p. Am J Cancer Res. 2018 Jan 1;8(1):39-55. eCollection 2018. Am J Cancer Res. 2018. PMID: 29416919 Free PMC article.

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