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miR-10b-5p is a novel Th17 regulator present in Th17 cells from ankylosing spondylitis.
Chen L, Al-Mossawi MH, Ridley A, Sekine T, Hammitzsch A, de Wit J, Simone D, Shi H, Penkava F, Kurowska-Stolarska M, Pulyakhina I, Knight JC, Kim TJ, Bowness P. Chen L, et al. Among authors: simone d. Ann Rheum Dis. 2017 Mar;76(3):620-625. doi: 10.1136/annrheumdis-2016-210175. Epub 2016 Dec 30. Ann Rheum Dis. 2017. PMID: 28039186
Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis.
Al-Mossawi MH, Chen L, Fang H, Ridley A, de Wit J, Yager N, Hammitzsch A, Pulyakhina I, Fairfax BP, Simone D, Yi Y, Bandyopadhyay S, Doig K, Gundle R, Kendrick B, Powrie F, Knight JC, Bowness P. Al-Mossawi MH, et al. Among authors: simone d. Nat Commun. 2017 Nov 15;8(1):1510. doi: 10.1038/s41467-017-01771-2. Nat Commun. 2017. PMID: 29142230 Free PMC article.
Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis.
Penkava F, Velasco-Herrera MDC, Young MD, Yager N, Nwosu LN, Pratt AG, Lara AL, Guzzo C, Maroof A, Mamanova L, Cole S, Efremova M, Simone D, Filer A, Brown CC, Croxford AL, Isaacs JD, Teichmann S, Bowness P, Behjati S, Hussein Al-Mossawi M. Penkava F, et al. Among authors: simone d. Nat Commun. 2020 Sep 21;11(1):4767. doi: 10.1038/s41467-020-18513-6. Nat Commun. 2020. PMID: 32958743 Free PMC article.
Increased interleukin-26 in the peripheral joints of patients with axial spondyloarthritis and psoriatic arthritis, co-localizing with CD68-positive synoviocytes.
Hammitzsch A, Ossadnik A, Bachmann Q, Merwald-Fraenk H, Lorenz G, Witt M, Wiesent F, Mühlhofer H, Simone D, Bowness P, Heemann U, Arbogast M, Moog P, Schmaderer C. Hammitzsch A, et al. Among authors: simone d. Front Immunol. 2024 May 10;15:1355824. doi: 10.3389/fimmu.2024.1355824. eCollection 2024. Front Immunol. 2024. PMID: 38799447 Free PMC article.
Elevated type-17 cytokines are present in axial spondyloarthritis stool.
Brough I, Thompson K, Latore C, Penkava F, Regan C, Pearson C, Shi H, Ridley A, Simone D, Lam L, Bullers S, Moussa C, Feeney R; Inflammatory Arthritis Microbiome Consortium (IAMC) Investigators Group; Al-Mossawi MH, Powrie F, Young S, Huttenhower C, Bowness P. Brough I, et al. Among authors: simone d. Discov Immunol. 2024 May 4;3(1):kyae005. doi: 10.1093/discim/kyae005. eCollection 2024. Discov Immunol. 2024. PMID: 38966778 Free PMC article.
Mucosal signatures of pathogenic T cells in HLA-B*27+ anterior uveitis and axial spondyloarthritis.
Paley MA, Yang X, Hassman LM, Penkava F, Garner LI, Paley GL, Linskey N, Agnew R, Arantes de Faria PH, Feng A, Li SY, Simone D, Roberson ED, Ruzycki PA, Esaulova E, Laurent J, Feigl-Lenzen L, Springer LE, Liu C, Gillespie GM, Bowness P, Garcia KC, Yokoyama WM. Paley MA, et al. Among authors: simone d. JCI Insight. 2024 Jul 18;9(16):e174776. doi: 10.1172/jci.insight.174776. JCI Insight. 2024. PMID: 39024572 Free PMC article.
Novel immune cell phenotypes in spondyloarthritis pathogenesis.
Mauro D, Simone D, Bucci L, Ciccia F. Mauro D, et al. Among authors: simone d. Semin Immunopathol. 2021 Apr;43(2):265-277. doi: 10.1007/s00281-021-00837-0. Epub 2021 Feb 10. Semin Immunopathol. 2021. PMID: 33569634 Free PMC article. Review.
310 results