Hughey JJ - Search Results

1

Combinatorial processing of bacterial and host-derived innate immune stimuli at the single-cell level.

Gutschow MV, Mason JC, Lane KM, Maayan I, Hughey JJ, Bajar BT, Amatya DN, Valle SD, Covert MW. Gutschow MV, et al. Among authors: hughey jj. Mol Biol Cell. 2019 Jan 15;30(2):282-292. doi: 10.1091/mbc.E18-07-0423. Epub 2018 Nov 21. Mol Biol Cell. 2019. PMID: 30462580 Free PMC article.

2

A noisy paracrine signal determines the cellular NF-kappaB response to lipopolysaccharide.

Lee TK, Denny EM, Sanghvi JC, Gaston JE, Maynard ND, Hughey JJ, Covert MW. Lee TK, et al. Among authors: hughey jj. Sci Signal. 2009 Oct 20;2(93):ra65. doi: 10.1126/scisignal.2000599. Sci Signal. 2009. PMID: 19843957 Free PMC article.

3

Single-cell NF-kappaB dynamics reveal digital activation and analogue information processing.

Tay S, Hughey JJ, Lee TK, Lipniacki T, Quake SR, Covert MW. Tay S, et al. Among authors: hughey jj. Nature. 2010 Jul 8;466(7303):267-71. doi: 10.1038/nature09145. Epub 2010 Jun 27. Nature. 2010. PMID: 20581820 Free PMC article.

4

Computational modeling of mammalian signaling networks.

Hughey JJ, Lee TK, Covert MW. Hughey JJ, et al. Wiley Interdiscip Rev Syst Biol Med. 2010 Mar-Apr;2(2):194-209. doi: 10.1002/wsbm.52. Wiley Interdiscip Rev Syst Biol Med. 2010. PMID: 20836022 Free PMC article. Review.

5

Single-cell and population NF-κB dynamic responses depend on lipopolysaccharide preparation.

Gutschow MV, Hughey JJ, Ruggero NA, Bajar BT, Valle SD, Covert MW. Gutschow MV, et al. Among authors: hughey jj. PLoS One. 2013;8(1):e53222. doi: 10.1371/journal.pone.0053222. Epub 2013 Jan 3. PLoS One. 2013. PMID: 23301045 Free PMC article.

6

High-sensitivity measurements of multiple kinase activities in live single cells.

Regot S, Hughey JJ, Bajar BT, Carrasco S, Covert MW. Regot S, et al. Among authors: hughey jj. Cell. 2014 Jun 19;157(7):1724-34. doi: 10.1016/j.cell.2014.04.039. Cell. 2014. PMID: 24949979 Free PMC article.

7

Single-cell variation leads to population invariance in NF-κB signaling dynamics.

Hughey JJ, Gutschow MV, Bajar BT, Covert MW. Hughey JJ, et al. Mol Biol Cell. 2015 Feb 1;26(3):583-90. doi: 10.1091/mbc.E14-08-1267. Epub 2014 Dec 3. Mol Biol Cell. 2015. PMID: 25473117 Free PMC article.

8

Live-cell measurements of kinase activity in single cells using translocation reporters.

Kudo T, Jeknić S, Macklin DN, Akhter S, Hughey JJ, Regot S, Covert MW. Kudo T, et al. Among authors: hughey jj. Nat Protoc. 2018 Jan;13(1):155-169. doi: 10.1038/nprot.2017.128. Epub 2017 Dec 21. Nat Protoc. 2018. PMID: 29266096

9

NF-κB signaling dynamics is controlled by a dose-sensing autoregulatory loop.

DeFelice MM, Clark HR, Hughey JJ, Maayan I, Kudo T, Gutschow MV, Covert MW, Regot S. DeFelice MM, et al. Among authors: hughey jj. Sci Signal. 2019 Apr 30;12(579):eaau3568. doi: 10.1126/scisignal.aau3568. Sci Signal. 2019. PMID: 31040261 Free PMC article.

10

MetaCyto: A Tool for Automated Meta-analysis of Mass and Flow Cytometry Data.

Hu Z, Jujjavarapu C, Hughey JJ, Andorf S, Lee HC, Gherardini PF, Spitzer MH, Thomas CG, Campbell J, Dunn P, Wiser J, Kidd BA, Dudley JT, Nolan GP, Bhattacharya S, Butte AJ. Hu Z, et al. Among authors: hughey jj. Cell Rep. 2018 Jul 31;24(5):1377-1388. doi: 10.1016/j.celrep.2018.07.003. Cell Rep. 2018. PMID: 30067990 Free PMC article.

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