Greve G - Search Results

1

Combination treatment of acute myeloid leukemia cells with DNMT and HDAC inhibitors: predominant synergistic gene downregulation associated with gene body demethylation.

Blagitko-Dorfs N, Schlosser P, Greve G, Pfeifer D, Meier R, Baude A, Brocks D, Plass C, Lübbert M. Blagitko-Dorfs N, et al. Among authors: greve g. Leukemia. 2019 Apr;33(4):945-956. doi: 10.1038/s41375-018-0293-8. Epub 2018 Nov 23. Leukemia. 2019. PMID: 30470836

2

Epigenetic priming of AML blasts for all-trans retinoic acid-induced differentiation by the HDAC class-I selective inhibitor entinostat.

Blagitko-Dorfs N, Jiang Y, Duque-Afonso J, Hiller J, Yalcin A, Greve G, Abdelkarim M, Hackanson B, Lübbert M. Blagitko-Dorfs N, et al. Among authors: greve g. PLoS One. 2013 Oct 8;8(10):e75258. doi: 10.1371/journal.pone.0075258. eCollection 2013. PLoS One. 2013. PMID: 24116031 Free PMC article.

3

Epigenetic priming of non-small cell lung cancer cell lines to the antiproliferative and differentiating effects of all-trans retinoic acid.

Greve G, Schiffmann I, Lübbert M. Greve G, et al. J Cancer Res Clin Oncol. 2015 Dec;141(12):2171-80. doi: 10.1007/s00432-015-1987-1. Epub 2015 May 26. J Cancer Res Clin Oncol. 2015. PMID: 26008188

4

The pan-HDAC inhibitor panobinostat acts as a sensitizer for erlotinib activity in EGFR-mutated and -wildtype non-small cell lung cancer cells.

Greve G, Schiffmann I, Pfeifer D, Pantic M, Schüler J, Lübbert M. Greve G, et al. BMC Cancer. 2015 Dec 16;15:947. doi: 10.1186/s12885-015-1967-5. BMC Cancer. 2015. PMID: 26675484 Free PMC article.

5

Epigenetic therapy approaches in non-small cell lung cancer: Update and perspectives.

Schiffmann I, Greve G, Jung M, Lübbert M. Schiffmann I, et al. Among authors: greve g. Epigenetics. 2016 Dec;11(12):858-870. doi: 10.1080/15592294.2016.1237345. Epub 2016 Nov 15. Epigenetics. 2016. PMID: 27846368 Free PMC article. Review.

6

Innovative strategies for adverse karyotype acute myeloid leukemia.

Blum S, Greve G, Lübbert M. Blum S, et al. Among authors: greve g. Curr Opin Hematol. 2017 Mar;24(2):89-98. doi: 10.1097/MOH.0000000000000318. Curr Opin Hematol. 2017. PMID: 28099271 Review.

7

Structure-activity studies on N-Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic cell differentiation.

Schulz-Fincke J, Hau M, Barth J, Robaa D, Willmann D, Kürner A, Haas J, Greve G, Haydn T, Fulda S, Lübbert M, Lüdeke S, Berg T, Sippl W, Schüle R, Jung M. Schulz-Fincke J, et al. Among authors: greve g. Eur J Med Chem. 2018 Jan 20;144:52-67. doi: 10.1016/j.ejmech.2017.12.001. Epub 2017 Dec 6. Eur J Med Chem. 2018. PMID: 29247860

8

LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML.

Barth J, Abou-El-Ardat K, Dalic D, Kurrle N, Maier AM, Mohr S, Schütte J, Vassen L, Greve G, Schulz-Fincke J, Schmitt M, Tosic M, Metzger E, Bug G, Khandanpour C, Wagner SA, Lübbert M, Jung M, Serve H, Schüle R, Berg T. Barth J, et al. Among authors: greve g. Leukemia. 2019 Jun;33(6):1411-1426. doi: 10.1038/s41375-018-0375-7. Epub 2019 Jan 24. Leukemia. 2019. PMID: 30679800

9

Identification of enhancer of mRNA decapping 4 as a novel fusion partner of MLL in acute myeloid leukemia.

Becker H, Greve G, Kataoka K, Mallm JP, Duque-Afonso J, Ma T, Niemöller C, Pantic M, Duyster J, Cleary ML, Schüler J, Rippe K, Ogawa S, Lübbert M. Becker H, et al. Among authors: greve g. Blood Adv. 2019 Mar 12;3(5):761-765. doi: 10.1182/bloodadvances.2018023879. Blood Adv. 2019. PMID: 30833276 Free PMC article.

10

Correction: LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML.

Barth J, Abou-El-Ardat K, Dalic D, Kurrle N, Maier AM, Mohr S, Schütte J, Vassen L, Greve G, Schulz-Fincke J, Schmitt M, Tosic M, Metzger E, Bug G, Khandanpour C, Wagner SA, Lübbert M, Jung M, Serve H, Schüle R, Berg T. Barth J, et al. Among authors: greve g. Leukemia. 2019 Jun;33(6):1541. doi: 10.1038/s41375-019-0415-y. Leukemia. 2019. PMID: 30837671

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