Janning P - Search Results

1

Target Engagement of Small Molecules: Thermal Profiling Approaches on Different Levels.

Reckzeh ES, Brockmeyer A, Metz M, Waldmann H, Janning P. Reckzeh ES, et al. Among authors: janning p. Methods Mol Biol. 2019;1888:73-98. doi: 10.1007/978-1-4939-8891-4_4. Methods Mol Biol. 2019. PMID: 30519941

2

Polyketides from the marine-derived fungus Ascochyta salicorniae and their potential to inhibit protein phosphatases.

Seibert SF, Eguereva E, Krick A, Kehraus S, Voloshina E, Raabe G, Fleischhauer J, Leistner E, Wiese M, Prinz H, Alexandrov K, Janning P, Waldmann H, König GM. Seibert SF, et al. Among authors: janning p. Org Biomol Chem. 2006 Jun 7;4(11):2233-40. doi: 10.1039/b601386d. Epub 2006 May 3. Org Biomol Chem. 2006. PMID: 16729132

3

Brunsvicamides A-C: sponge-related cyanobacterial peptides with Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory activity.

Müller D, Krick A, Kehraus S, Mehner C, Hart M, Küpper FC, Saxena K, Prinz H, Schwalbe H, Janning P, Waldmann H, König GM. Müller D, et al. Among authors: janning p. J Med Chem. 2006 Aug 10;49(16):4871-8. doi: 10.1021/jm060327w. J Med Chem. 2006. PMID: 16884299

4

The Ras pathway modulator melophlin A targets dynamins.

Knoth T, Warburg K, Katzka C, Rai A, Wolf A, Brockmeyer A, Janning P, Reubold TF, Eschenburg S, Manstein DJ, Hübel K, Kaiser M, Waldmann H. Knoth T, et al. Among authors: janning p. Angew Chem Int Ed Engl. 2009;48(39):7240-5. doi: 10.1002/anie.200902023. Angew Chem Int Ed Engl. 2009. PMID: 19722243 No abstract available.

5

Identification of Ustilago maydis Aurora kinase as a novel antifungal target.

Tückmantel S, Greul JN, Janning P, Brockmeyer A, Grütter C, Simard JR, Gutbrod O, Beck ME, Tietjen K, Rauh D, Schreier PH. Tückmantel S, et al. Among authors: janning p. ACS Chem Biol. 2011 Sep 16;6(9):926-33. doi: 10.1021/cb200112y. Epub 2011 Jun 20. ACS Chem Biol. 2011. PMID: 21671622

6

Expanded click conjugation of recombinant proteins with ubiquitin-like modifiers reveals altered substrate preference of SUMO2-modified Ubc9.

Sommer S, Weikart ND, Brockmeyer A, Janning P, Mootz HD. Sommer S, et al. Among authors: janning p. Angew Chem Int Ed Engl. 2011 Oct 10;50(42):9888-92. doi: 10.1002/anie.201102531. Epub 2011 Sep 7. Angew Chem Int Ed Engl. 2011. PMID: 21898723

7

Identification of acyl protein thioesterases 1 and 2 as the cellular targets of the Ras-signaling modulators palmostatin B and M.

Rusch M, Zimmermann TJ, Bürger M, Dekker FJ, Görmer K, Triola G, Brockmeyer A, Janning P, Böttcher T, Sieber SA, Vetter IR, Hedberg C, Waldmann H. Rusch M, et al. Among authors: janning p. Angew Chem Int Ed Engl. 2011 Oct 10;50(42):9838-42. doi: 10.1002/anie.201102967. Epub 2011 Sep 9. Angew Chem Int Ed Engl. 2011. PMID: 21905186

8

Natural product-inspired cascade synthesis yields modulators of centrosome integrity.

Dückert H, Pries V, Khedkar V, Menninger S, Bruss H, Bird AW, Maliga Z, Brockmeyer A, Janning P, Hyman A, Grimme S, Schürmann M, Preut H, Hübel K, Ziegler S, Kumar K, Waldmann H. Dückert H, et al. Among authors: janning p. Nat Chem Biol. 2011 Dec 25;8(2):179-84. doi: 10.1038/nchembio.758. Nat Chem Biol. 2011. PMID: 22198731

9

Minimally invasive mutagenesis gives rise to a biosynthetic polyketide library.

Kushnir S, Sundermann U, Yahiaoui S, Brockmeyer A, Janning P, Schulz F. Kushnir S, et al. Among authors: janning p. Angew Chem Int Ed Engl. 2012 Oct 15;51(42):10664-9. doi: 10.1002/anie.201202438. Epub 2012 Sep 20. Angew Chem Int Ed Engl. 2012. PMID: 22996590

10

A natural product inspired tetrahydropyran collection yields mitosis modulators that synergistically target CSE1L and tubulin.

Voigt T, Gerding-Reimers C, Ngoc Tran TT, Bergmann S, Lachance H, Schölermann B, Brockmeyer A, Janning P, Ziegler S, Waldmann H. Voigt T, et al. Among authors: janning p. Angew Chem Int Ed Engl. 2013 Jan 2;52(1):410-4. doi: 10.1002/anie.201205728. Epub 2012 Oct 18. Angew Chem Int Ed Engl. 2013. PMID: 23080551

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