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Synthesis of Indomorphan Pseudo-Natural Product Inhibitors of Glucose Transporters GLUT-1 and -3.
Ceballos J, Schwalfenberg M, Karageorgis G, Reckzeh ES, Sievers S, Ostermann C, Pahl A, Sellstedt M, Nowacki J, Carnero Corrales MA, Wilke J, Laraia L, Tschapalda K, Metz M, Sehr DA, Brand S, Winklhofer K, Janning P, Ziegler S, Waldmann H. Ceballos J, et al. Among authors: pahl a. Angew Chem Int Ed Engl. 2019 Nov 18;58(47):17016-17025. doi: 10.1002/anie.201909518. Epub 2019 Oct 7. Angew Chem Int Ed Engl. 2019. PMID: 31469221 Free PMC article.
A Scaffold-Diversity Synthesis of Biologically Intriguing Cyclic Sulfonamides.
Zimmermann S, Akbarzadeh M, Otte F, Strohmann C, Sankar MG, Ziegler S, Pahl A, Sievers S, Kumar K. Zimmermann S, et al. Among authors: pahl a. Chemistry. 2019 Dec 5;25(68):15498-15503. doi: 10.1002/chem.201904175. Epub 2019 Nov 7. Chemistry. 2019. PMID: 31518018 Free PMC article.
Identification of Quinolinols as Activators of TEAD-Dependent Transcription.
Pobbati AV, Mejuch T, Chakraborty S, Karatas H, Bharath SR, Guéret SM, Goy PA, Hahne G, Pahl A, Sievers S, Guccione E, Song H, Waldmann H, Hong W. Pobbati AV, et al. Among authors: pahl a. ACS Chem Biol. 2019 Dec 20;14(12):2909-2921. doi: 10.1021/acschembio.9b00786. Epub 2019 Dec 2. ACS Chem Biol. 2019. PMID: 31742995 Free article.
Image-Based Morphological Profiling Identifies a Lysosomotropic, Iron-Sequestering Autophagy Inhibitor.
Laraia L, Garivet G, Foley DJ, Kaiser N, Müller S, Zinken S, Pinkert T, Wilke J, Corkery D, Pahl A, Sievers S, Janning P, Arenz C, Wu Y, Rodriguez R, Waldmann H. Laraia L, et al. Among authors: pahl a. Angew Chem Int Ed Engl. 2020 Mar 27;59(14):5721-5729. doi: 10.1002/anie.201913712. Epub 2020 Jan 24. Angew Chem Int Ed Engl. 2020. PMID: 31769920 Free PMC article.
Discovery of Covalent Inhibitors Targeting the Transcriptional Enhanced Associate Domain Central Pocket.
Karatas H, Akbarzadeh M, Adihou H, Hahne G, Pobbati AV, Yihui Ng E, Guéret SM, Sievers S, Pahl A, Metz M, Zinken S, Dötsch L, Nowak C, Thavam S, Friese A, Kang C, Hong W, Waldmann H. Karatas H, et al. Among authors: pahl a. J Med Chem. 2020 Oct 22;63(20):11972-11989. doi: 10.1021/acs.jmedchem.0c01275. Epub 2020 Oct 1. J Med Chem. 2020. PMID: 32907324 Free PMC article.
166 results