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Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus.
Kyriakou E, Schmidt S, Dodd GT, Pfuhlmann K, Simonds SE, Lenhart D, Geerlof A, Schriever SC, De Angelis M, Schramm KW, Plettenburg O, Cowley MA, Tiganis T, Tschöp MH, Pfluger PT, Sattler M, Messias AC. Kyriakou E, et al. Among authors: pfluger pt. J Med Chem. 2018 Dec 27;61(24):11144-11157. doi: 10.1021/acs.jmedchem.8b01224. Epub 2018 Dec 7. J Med Chem. 2018. PMID: 30525586
Effects of obestatin on energy balance and growth hormone secretion in rodents.
Nogueiras R, Pfluger P, Tovar S, Arnold M, Mitchell S, Morris A, Perez-Tilve D, Vázquez MJ, Wiedmer P, Castañeda TR, DiMarchi R, Tschöp M, Schurmann A, Joost HG, Williams LM, Langhans W, Diéguez C. Nogueiras R, et al. Endocrinology. 2007 Jan;148(1):21-6. doi: 10.1210/en.2006-0915. Epub 2006 Sep 28. Endocrinology. 2007. PMID: 17008393
Bsx, a novel hypothalamic factor linking feeding with locomotor activity, is regulated by energy availability.
Nogueiras R, López M, Lage R, Perez-Tilve D, Pfluger P, Mendieta-Zerón H, Sakkou M, Wiedmer P, Benoit SC, Datta R, Dong JZ, Culler M, Sleeman M, Vidal-Puig A, Horvath T, Treier M, Diéguez C, Tschöp MH. Nogueiras R, et al. Endocrinology. 2008 Jun;149(6):3009-15. doi: 10.1210/en.2007-1684. Epub 2008 Feb 28. Endocrinology. 2008. PMID: 18308842 Free PMC article.
Gastric O-acyl transferase activates hunger signal to the brain.
Tong J, Pfluger PT, Tschöp MH. Tong J, et al. Among authors: pfluger pt. Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6213-4. doi: 10.1073/pnas.0802461105. Epub 2008 Apr 28. Proc Natl Acad Sci U S A. 2008. PMID: 18443299 Free PMC article. No abstract available.
Long-term effects of ghrelin and ghrelin receptor agonists on energy balance in rats.
Strassburg S, Anker SD, Castaneda TR, Burget L, Perez-Tilve D, Pfluger PT, Nogueiras R, Halem H, Dong JZ, Culler MD, Datta R, Tschöp MH. Strassburg S, et al. Among authors: pfluger pt. Am J Physiol Endocrinol Metab. 2008 Jul;295(1):E78-84. doi: 10.1152/ajpendo.00040.2008. Epub 2008 May 6. Am J Physiol Endocrinol Metab. 2008. PMID: 18460598 Free PMC article.
Sirt1 protects against high-fat diet-induced metabolic damage.
Pfluger PT, Herranz D, Velasco-Miguel S, Serrano M, Tschöp MH. Pfluger PT, et al. Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9793-8. doi: 10.1073/pnas.0802917105. Epub 2008 Jul 3. Proc Natl Acad Sci U S A. 2008. PMID: 18599449 Free PMC article.
133 results