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Targeting the DNA Repair Endonuclease ERCC1-XPF with Green Tea Polyphenol Epigallocatechin-3-Gallate (EGCG) and Its Prodrug to Enhance Cisplatin Efficacy in Human Cancer Cells.
Heyza JR, Arora S, Zhang H, Conner KL, Lei W, Floyd AM, Deshmukh RR, Sarver J, Trabbic CJ, Erhardt P, Chan TH, Dou QP, Patrick SM. Heyza JR, et al. Among authors: patrick sm. Nutrients. 2018 Nov 3;10(11):1644. doi: 10.3390/nu10111644. Nutrients. 2018. PMID: 30400270 Free PMC article.
APOBEC3 enzymes mediate efficacy of cisplatin and are epistatic with base excision repair and mismatch repair in platinum response.
Conner KL, Shaik AN, Marshall KA, Floyd AM, Ekinci E, Lindquist J, Sawant A, Lei W, Adolph MB, Chelico L, Siriwardena SU, Bhagwat A, Kim S, Cote ML, Patrick SM. Conner KL, et al. Among authors: patrick sm. NAR Cancer. 2020 Dec;2(4):zcaa033. doi: 10.1093/narcan/zcaa033. Epub 2020 Nov 6. NAR Cancer. 2020. PMID: 33196045 Free PMC article.
68 results