Ouyang SX - Search Results

1

Allosteric Inhibition of Ubiquitin-like Modifications by a Class of Inhibitor of SUMO-Activating Enzyme.

Li YJ, Du L, Wang J, Vega R, Lee TD, Miao Y, Aldana-Masangkay G, Samuels ER, Li B, Ouyang SX, Colayco SA, Bobkova EV, Divlianska DB, Sergienko E, Chung TDY, Fakih M, Chen Y. Li YJ, et al. Among authors: ouyang sx. Cell Chem Biol. 2019 Feb 21;26(2):278-288.e6. doi: 10.1016/j.chembiol.2018.10.026. Epub 2018 Dec 20. Cell Chem Biol. 2019. PMID: 30581133 Free PMC article.

2

Critical Non-Covalent Binding Intermediate for an Allosteric Covalent Inhibitor of SUMO E1.

Pawnikar S, Bhattarai A, Ouyang SX, Vega R, Chen Y, Miao Y. Pawnikar S, et al. Among authors: ouyang sx. J Phys Chem Lett. 2023 Mar 23;14(11):2792-2799. doi: 10.1021/acs.jpclett.3c00253. Epub 2023 Mar 10. J Phys Chem Lett. 2023. PMID: 36898086 Free PMC article.

3

Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation.

Wang J, Luo C, Shan C, You Q, Lu J, Elf S, Zhou Y, Wen Y, Vinkenborg JL, Fan J, Kang H, Lin R, Han D, Xie Y, Karpus J, Chen S, Ouyang S, Luan C, Zhang N, Ding H, Merkx M, Liu H, Chen J, Jiang H, He C. Wang J, et al. Nat Chem. 2015 Dec;7(12):968-79. doi: 10.1038/nchem.2381. Epub 2015 Nov 9. Nat Chem. 2015. PMID: 26587712 Free PMC article.

4

Author Correction: Pro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence.

Sun DY, Wu WB, Wu JJ, Shi Y, Xu JJ, Ouyang SX, Chi C, Shi Y, Ji QX, Miao JH, Fu JT, Tong J, Zhang PP, Zhang JB, Li ZY, Qu LF, Shen FM, Li DJ, Wang P. Sun DY, et al. Among authors: ouyang sx. Nat Commun. 2024 Nov 14;15(1):9874. doi: 10.1038/s41467-024-54088-2. Nat Commun. 2024. PMID: 39543124 Free PMC article. No abstract available.

5

Gasdermin-E-mediated pyroptosis drives immune checkpoint inhibitor-associated myocarditis via cGAS-STING activation.

Sun SJ, Jiao XD, Chen ZG, Cao Q, Zhu JH, Shen QR, Liu Y, Zhang Z, Xu FF, Shi Y, Tong J, Ouyang SX, Fu JT, Zhao Y, Ren J, Li DJ, Shen FM, Wang P. Sun SJ, et al. Among authors: ouyang sx. Nat Commun. 2024 Aug 5;15(1):6640. doi: 10.1038/s41467-024-50996-5. Nat Commun. 2024. PMID: 39103324 Free PMC article.

6

GSDME promotes MASLD by regulating pyroptosis, Drp1 citrullination-dependent mitochondrial dynamic, and energy balance in intestine and liver.

Zhu JH, Ouyang SX, Zhang GY, Cao Q, Xin R, Yin H, Wu JW, Zhang Y, Zhang Z, Liu Y, Fu JT, Chen YT, Tong J, Zhang JB, Liu J, Shen FM, Li DJ, Wang P. Zhu JH, et al. Among authors: ouyang sx. Cell Death Differ. 2024 Nov;31(11):1467-1486. doi: 10.1038/s41418-024-01343-0. Epub 2024 Jul 16. Cell Death Differ. 2024. PMID: 39009654

7

Gasdermin-E-Dependent Non-Canonical Pyroptosis Promotes Drug-Induced Liver Failure by Promoting CPS1 deISGylation and Degradation.

Ouyang SX, Zhu JH, Cao Q, Liu J, Zhang Z, Zhang Y, Wu JW, Sun SJ, Fu JT, Chen YT, Tong J, Liu Y, Zhang JB, Shen FM, Li DJ, Wang P. Ouyang SX, et al. Adv Sci (Weinh). 2024 Apr;11(16):e2305715. doi: 10.1002/advs.202305715. Epub 2024 Feb 28. Adv Sci (Weinh). 2024. PMID: 38417117 Free PMC article.

8

Pro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence.

Sun DY, Wu WB, Wu JJ, Shi Y, Xu JJ, Ouyang SX, Chi C, Shi Y, Ji QX, Miao JH, Fu JT, Tong J, Zhang PP, Zhang JB, Li ZY, Qu LF, Shen FM, Li DJ, Wang P. Sun DY, et al. Among authors: ouyang sx. Nat Commun. 2024 Feb 16;15(1):1429. doi: 10.1038/s41467-024-45823-w. Nat Commun. 2024. PMID: 38365899 Free PMC article.

9

Sting mutation attenuates acetaminophen-induced acute liver injury by limiting NLRP3 activation.

Li ZC, Xu FF, Fu JT, Ouyang SX, Cao Q, Yan YY, Li DJ, Shen FM, Ni M. Li ZC, et al. Among authors: ouyang sx. Int Immunopharmacol. 2023 Dec;125(Pt A):111133. doi: 10.1016/j.intimp.2023.111133. Epub 2023 Oct 27. Int Immunopharmacol. 2023. PMID: 38149573

10

Ferroptosis inhibitor liproxstatin-1 alleviates metabolic dysfunction-associated fatty liver disease in mice: potential involvement of PANoptosis.

Tong J, Lan XT, Zhang Z, Liu Y, Sun DY, Wang XJ, Ou-Yang SX, Zhuang CL, Shen FM, Wang P, Li DJ. Tong J, et al. Acta Pharmacol Sin. 2023 May;44(5):1014-1028. doi: 10.1038/s41401-022-01010-5. Epub 2022 Nov 2. Acta Pharmacol Sin. 2023. PMID: 36323829 Free PMC article.

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