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Nanostructures of diamond, graphene oxide and graphite inhibit CYP1A2, CYP2D6 and CYP3A4 enzymes and downregulate their genes in liver cells.
Strojny B, Sawosz E, Grodzik M, Jaworski S, Szczepaniak J, Sosnowska M, Wierzbicki M, Kutwin M, Orlińska S, Chwalibog A. Strojny B, et al. Among authors: orlinska s. Int J Nanomedicine. 2018 Dec 13;13:8561-8575. doi: 10.2147/IJN.S188997. eCollection 2018. Int J Nanomedicine. 2018. PMID: 30587978 Free PMC article.